acetylcholine

/əˌsitəlˈkoʊlin/

//əˌsitəlˈkoʊlin// noun

Detailed reference entry for the English word "acetylcholine", 13-letters, with pronunciation in International Phonetic Alphabet notation, etymology traced through Germanic and Romance roots where applicable, common misspelling variants catalogued from Wiktionary, and usage frequency ranked against an open word-frequency list covering the top 100,000 English words. PlainSpell covers English, Spanish, Portuguese, French, and German spelling with confusable-pair detection that highlights visually and phonetically similar words. This entry for "acetylcholine" includes synonyms, antonyms, homophones, and cross-language translation pointers sourced from Wiktionary via the kaikki.org extract. Whether you are verifying the correct spelling of "acetylcholine" for academic writing, checking homophone confusion, or exploring etymological origins, this page provides a citation-backed, free reference that requires no sign-up.

The verdict

“acetylcholine” is a moderately-common English word, ranked #46,887 in English word frequency and used as a noun.

#46,887
frequency rank, English
13
letters
20
tracked misspellings

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - A neurotransmitter in humans and other animals. It is an ester of acetic acid and choline with chemical formula CH₃COOCH₂CH₂N⁺(CH₃)₃.

Compare similar words

See how acetylcholine compares against similar English words.

Browse all word comparisons →
Key facts for acetylcholine
PropertyValue
Headwordacetylcholine
LanguageEnglish
Part of speechNoun
IPA/əˌsitəlˈkoʊlin/
Letters13
Frequency rank#46,887
Misspellings tracked20
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “acetylcholine” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). acetylcholine lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Spelling & Dictionary Insight

The English entry for acetylcholine is 13 letters long, classified as a noun, and transcribed in the International Phonetic Alphabet as /əˌsitəlˈkoʊlin/. Corpus data places it at rank #46,887 in overall English word frequency, marking it as uncommon enough that many writers pause before typing it. The dominant gloss from Wiktionary reads: "A neurotransmitter in humans and other animals. It is an ester of acetic acid and choline with chemical formula CH₃COOCH₂CH₂N⁺(CH₃)₃.".

Our generated misspelling index lists 20 likely wrong-spelling variants for acetylcholine, with forms such as "accetylcholine", "acetlycholine", and "acettylcholine". Each variant is a distinct typo pattern an edit-distance generator flags, typically a doubled-consonant error, a silent-letter drop, or a vowel substitution. It is not paired with a close-neighbour confusable in our dataset, which tends to mean the word is visually distinctive enough to stand on its own.

No explicit etymology string is stored for this entry, so spelling patterns must be inferred from the word's phoneme-to-grapheme mapping rather than from a documented borrowing chain. For readers arriving here from a spelling check, the authoritative guidance is: the correct English form is acetylcholine, spelled A-C-E-T-Y-L-C-H-O-L-I-N-E, and any other sequence of those letters, regardless of how natural it feels, is a misspelling in standard orthography.

Definition

  1. 1
    A neurotransmitter in humans and other animals. It is an ester of acetic acid and choline with chemical formula CH₃COOCH₂CH₂N⁺(CH₃)₃.

This word in other languages

Common misspellings

Also misspelled as: accetylcholine,acetlycholine,acettylcholine,acetyclholine,acetylccholine,acetylchholine,acetylchloine,acetylchoilne,acetylcholien,acetylcholinne,acetylcholline,acetylcholnie,acetylcohline,acetylhcoline,acetyllcholine,acetyylcholine,aceytlcholine,acteylcholine,aectylcholine,caetylcholine

Misspelling Pattern Breakdown

How far each generated variant is from the correct spelling of acetylcholine - measured in single-character edits (insert, delete, or substitute a letter). Larger bars are easier to catch; one-edit slips are the sneakiest.

accetylcholine1acetlycholine2acettylcholine1acetyclholine2acetylccholine1acetylchholine1acetylchloine2acetylchoilne2
Edit distance from "acetylcholine"

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Cite this page

Free to reuse with attribution (CC BY-SA). Copy the citation:

PlainSpell, “acetylcholine, English word data” (May 6, 2026). Derived from Wiktionary (kaikki.org, CC BY-SA) and an open word-frequency list. https://plainspell.com/en/word/acetylcholine

Frequently Asked Questions

How do you spell "acetylcholine"?
"acetylcholine" is spelled A-C-E-T-Y-L-C-H-O-L-I-N-E. The IPA pronunciation is /əˌsitəlˈkoʊlin/.
What does "acetylcholine" mean?
As a noun, "acetylcholine" means: A neurotransmitter in humans and other animals. It is an ester of acetic acid and choline with chemical formula CH₃COOCH₂CH₂N⁺(CH₃)₃.
What are common misspellings of "acetylcholine"?
Common misspellings include "accetylcholine", "acetlycholine", "acettylcholine", "acetyclholine", "acetylccholine". The correct spelling is "acetylcholine".
How do you pronounce "acetylcholine"?
The IPA (International Phonetic Alphabet) transcription for "acetylcholine" is /əˌsitəlˈkoʊlin/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What language does "acetylcholine" come from?
"acetylcholine" is a English word. PlainSpell covers definitions, pronunciations, and spelling data across English, Spanish, Portuguese, French, and German.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “acetylcholine”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is A-C-E-T-Y-L-C-H-O-L-I-N-E - every other letter order is a misspelling in standard orthography.
  • Say it as /əˌsitəlˈkoʊlin/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words

Nearby English words

Other entries that begin with the letter A in our English index:

Explore PlainSpell

Data Source: Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list FrequencyWords open word-frequency list