acetylcholinesterase
"acetylcholinesterase" is a 20-letter English headword indexed on PlainSpell.
The verdict
“acetylcholinesterase” is uncommon English (frequency #96,713 among 3,931 “A” headwords), classed as a noun. The kind of spelling people second-guess.
- #96,713
- frequency rank, English
- 3,931
- “A” headwords
According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - An enzyme that catalyzes the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid.
Corpus desk
Index EN-acetylcholinesterase · acetylcholinesterase · English
acetylcholinesterase · rank #96,713 · 0 variants · 0 confusables
- FREQ-RARE #96,713
- LEN-MEGA 20 letters
- VOW-9 9 vowels
- CONFUS-0 No pairs
- VAR-0 0 variants
- BOOK-MID 3,931
- PHOTO-FINISH accumulative
Nearest frequency peer: accumulative (-2 rank slots)
Read with this headword: Spelling guide for this pattern
Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.
Long-tail ranks near “acetylcholinesterase”
Sparse band: bars invert rank so rarer forms read shorter
- accumulative
accumulative
3,290 corpus weight
- acetylcholi…
acetylcholinesterase
3,288 corpus weight
- advocaat
advocaat
3,286 corpus weight
- aflatoxin
aflatoxin
3,281 corpus weight
- agama
agama
3,280 corpus weight
- agriculturi…
agriculturist
3,278 corpus weight
What this shows Long-tail view: where “acetylcholinesterase” sits against similarly uncommon English ranks.
| Property | Value |
|---|---|
| Headword | acetylcholinesterase |
| Language | English |
| Part of speech | Noun |
| Letters | 20 |
| Frequency rank | #96,713 |
| Misspellings tracked | 0 |
| Confusable pairs | 0 |
| Source | Wiktionary (kaikki.org) |
Long-tail rank of “acetylcholinesterase” in English
Rare enough to double-check
acetylcholinesterase is uncommon English at frequency #96,713 among 3,931 “A” headwords, classed as anoun. Rarity is why readers land here mid-draft. Gloss: "An enzyme that catalyzes the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid.".
The misspelling generator found no plausible variants for acetylcholinesterase, typically a sign the spelling maps closely to how the word sounds. Our dataset records no confusable match here, a sign it's visually distinctive enough not to be mixed up with another word.
Etymologically, the entry records: From acetylcholine + esterase. The correct English form is acetylcholinesterase, spelled A-C-E-T-Y-L-C-H-O-L-I-N-E-S-T-E-R-A-S-E.
Definition
- 1An enzyme that catalyzes the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid.
Etymology
From acetylcholine + esterase.
This word in other languages
Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.
Frequently Asked Questions
How do you spell "acetylcholinesterase"?
What does "acetylcholinesterase" mean?
What is the origin of the word "acetylcholinesterase"?
Is PlainSpell free to use?
Similar English words by spelling shape
Same letter count and similar misspelling depth for "acetylcholinesterase", not the corpus desk frequency band.
Same letter count
Frequency-ranked English headwords with 20 letters (nearest by frequency rank).