acetylcholinesterase
"acetylcholinesterase" is a 20-letter English headword indexed on PlainSpell.
The verdict
“acetylcholinesterase” is an uncommon English word, ranked #96,713 in English word frequency and used as a noun.
- #96,713
- frequency rank, English
- 20
- letters
According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - An enzyme that catalyzes the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid.
| Property | Value |
|---|---|
| Headword | acetylcholinesterase |
| Language | English |
| Part of speech | Noun |
| Letters | 20 |
| Frequency rank | #96,713 |
| Misspellings tracked | 0 |
| Confusable pairs | 0 |
| Source | Wiktionary (kaikki.org) |
Where “acetylcholinesterase” sits in English frequency
Spelling & Dictionary Insight
The English entry for acetylcholinesterase is 20 letters long, classified as a noun. Corpus data places it at rank #96,713 in overall English word frequency, marking it as uncommon enough that many writers pause before typing it. The dominant gloss from Wiktionary reads: "An enzyme that catalyzes the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid.".
The misspelling generator found no plausible variants for acetylcholinesterase, typically a sign the spelling maps closely to how the word sounds. Our dataset records no confusable match here, a sign it's visually distinctive enough not to be mixed up with another word.
Etymologically, the entry records: From acetylcholine + esterase. The correct English form is acetylcholinesterase, spelled A-C-E-T-Y-L-C-H-O-L-I-N-E-S-T-E-R-A-S-E.
Definition
- 1An enzyme that catalyzes the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid.
Etymology
From acetylcholine + esterase.
This word in other languages
Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.
Frequently Asked Questions
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Using “acetylcholinesterase”
The practical upshot for anyone who landed here from a spell-check.
- The one correct English spelling is A-C-E-T-Y-L-C-H-O-L-I-N-E-S-T-E-R-A-S-E - every other letter order is a misspelling in standard orthography.
- Browse more English words and confusable pairs in the same reference. English words
Data Source
Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.