choline
/ˈkoʊliːn/
"choline" is a 7-letter English headword indexed on PlainSpell.
The verdict
“choline” is uncommon English (frequency #55,325 among 5,599 “C” headwords), classed as a noun. The kind of spelling people second-guess.
- #55,325
- frequency rank, English
- 5,599
- “C” headwords
According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - A hydroxy quaternary ammonium compound with formula (CH₃)₃N⁺CH₂CH₂OHX⁻. It is an essential nutrient for cardiovascular and brain health and for cell membrane formation.
Corpus desk
Index EN-choline · choline · English
choline · rank #55,325 · 0 variants · 0 confusables
- FREQ-RARE #55,325
- LEN-LONG 7 letters
- VOW-3 3 vowels
- CONFUS-0 No pairs
- VAR-0 0 variants
- BOOK-DENSE 5,599
- PHOTO-FINISH chinaman
Nearest frequency peer: chinaman (-1 rank slots)
Read with this headword: Spelling guide for this pattern
Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.
Long-tail ranks near “choline”
Sparse band: bars invert rank so rarer forms read shorter
- Cheech
Cheech
44,680 corpus weight
- cheeked
cheeked
44,679 corpus weight
- chih
chih
44,678 corpus weight
- chinaman
chinaman
44,677 corpus weight
- choline
choline
44,676 corpus weight
- circumspect
circumspect
44,674 corpus weight
What this shows Long-tail view: where “choline” sits against similarly uncommon English ranks.
| Property | Value |
|---|---|
| Headword | choline |
| Language | English |
| Part of speech | Noun |
| IPA | /ˈkoʊliːn/ |
| Letters | 7 |
| Frequency rank | #55,325 |
| Misspellings tracked | 0 |
| Confusable pairs | 0 |
| Source | Wiktionary (kaikki.org) |
Long-tail rank of “choline” in English
Rare enough to double-check
choline is uncommon English at frequency #55,325 among 5,599 “C” headwords, classed as anoun, transcribed /ˈkoʊliːn/. Rarity is why readers land here mid-draft. Gloss: "A hydroxy quaternary ammonium compound with formula (CH₃)₃N⁺CH₂CH₂OHX⁻. It is an essential nutrient for cardiovascular and brain health and for cell membrane formation.".
choline doesn't appear in our generated misspelling index, suggesting the orthography follows predictable English patterns. No close-neighbour confusable shows up for this headword in our dataset, which tends to mean the word is visually distinctive enough to stand on its own.
Etymologically, the entry records: Coined from Ancient Greek χολή (kholḗ, “bile”). The chemical compound was first isolated by Adolph Strecker from pig and ox bile (hence the name) in 1862. It was also named neurine when chemically synthesized by Oscar Liebreich in 1865, until 1898 when show… The correct English form is choline, spelled C-H-O-L-I-N-E.
Definition
- 1A hydroxy quaternary ammonium compound with formula (CH₃)₃N⁺CH₂CH₂OHX⁻. It is an essential nutrient for cardiovascular and brain health and for cell membrane formation.
Etymology
Coined from Ancient Greek χολή (kholḗ, “bile”). The chemical compound was first isolated by Adolph Strecker from pig and ox bile (hence the name) in 1862. It was also named neurine when chemically synthesized by Oscar Liebreich in 1865, until 1898 when shown to be identical to choline.
Synonyms
This word in other languages
Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.
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Similar English words by spelling shape
Same letter count and similar misspelling depth for "choline", not the corpus desk frequency band.
Same letter count
Frequency-ranked English headwords with 7 letters (nearest by frequency rank).