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Sterilisation or sterilization?

In American English write sterilization; in British and Commonwealth English, sterilisation. sterilisation is a noun meaning “Non-Oxford British English standard spelling of sterilization”; sterilization is a noun meaning “The process of treating something to kill or inactivate microorganisms”. In written English (wordfreq, 2021 data) sterilization is about 5.1 times as common as sterilisation.

sterilisationorsterilization

What is the difference between sterilisation and sterilization?

sterilisationsterilization
Part of speechnounnoun
Meaning

BritishUSThe process of treating something to kill or inactivate microorganisms

BritishUSA procedure to permanently prevent an organism from reproducing

Examplenone recordedHeat sterilization is used during canning so the food can be safely stored for long periods
Formssterilisationssterilizations
Pronunciationnot recordednot recorded
RegionUKUK, US
In writingabout once in every 4 million words1.3 times per million words

Sources: sterilisation and sterilization in the English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0); written frequency: wordfreq 3.1 (a 2021 snapshot of Wikipedia, subtitles, news, books, web text and social media).

Every current meaning of sterilisation and sterilization

sterilization

  1. 1

    noun BritishUSThe process of treating something to kill or inactivate microorganisms

    Heat sterilization is used during canning so the food can be safely stored for long periods

  2. 2

    noun BritishUSA procedure to permanently prevent an organism from reproducing

    Spaying a cat is a form of sterilization to limit the population growth

  3. 3

    noun BritishUSAn instance of a sterilization procedure

    The vet performed several sterilizations this week

  4. 4

    noun BritishUSA monetary policy operation used to offset a foreign exchange intervention

    The Federal Reserve is responsible for foreign exchange sterilization

  5. 5

    noun BritishUSThe process of permanently rendering a planet like Earth completely uninhabitable to all life, including even microbes, leading to their complete extinction

    In about 1 billion years, the increasing heat from the Sun as it gradually ages, by triggering a runaway greenhouse effect that will boil away the oceans, will lead to the…

Source: the English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0); obsolete, archaic, dialect and rare senses left out.

Which is more common, sterilisation or sterilization?

sterilisation appears about once in every 4 million words; sterilization 1.3 times per million words.

Source: written frequency: wordfreq 3.1 (a 2021 snapshot of Wikipedia, subtitles, news, books, web text and social media).

How many people search sterilisation vs sterilization?

“sterilisation vs sterilization” is searched about 20 times a month on Google (Bing reports no separate figure) in the United States. Google counts close variants of a query together (“sterilization vs sterilisation”, “sterilisation or sterilization”).

Sources: Google Ads keyword data through DataForSEO and Microsoft Advertising keyword data through DataForSEO, the average month from September 2025 to August 2026.

The words