méthotrexate

\me.to.tʁak.sat\

/\me.to.tʁak.sat\/ noun

The verdict

“méthotrexate” is uncommon French (outside the top frequency list), classed as a noun. The kind of spelling people second-guess.

Unranked
below top-frequency French
12
letters

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - Antimétabolite utilisé dans le traitement de certaines maladies.

Corpus desk

Index FR-methotrexate · méthotrexate · French

méthotrexate · unranked · 0 variants · 0 confusables

  • FREQ-UNRANKED Unranked
  • LEN-MEGA 12 letters
  • VOW-5 5 vowels
  • CONFUS-0 No pairs
  • VAR-0 0 variants
  • BOOK-THIN "M" thin
  • PHOTO-UNK Peer pending

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Key facts for méthotrexate
PropertyValue
Headwordméthotrexate
LanguageFrench
Part of speechNoun
IPA\me.to.tʁak.sat\
Letters12
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “méthotrexate” sits in French frequency

méthotrexate falls outside the top-100,000 ranked French words, the long-tail zone of technical, archaic, or low-frequency vocabulary, exactly where readers second-guess spellings most.

Beyond rank #100,000. Source: FrequencyWords open word-frequency list.

Rare enough to double-check

méthotrexate is uncommon French outside the top frequency list, classed as anoun, transcribed \me.to.tʁak.sat\. Rarity is why readers land here mid-draft. Gloss: "Antimétabolite utilisé dans le traitement de certaines maladies.".

No misspelling variants are generated for méthotrexate in our index, since its letter pattern doesn't lend itself to common typo substitutions. It is not paired with a close-neighbour confusable in our dataset, which tends to mean the word is visually distinctive enough to stand on its own.

Our source data has no etymology on file for this entry, so spelling patterns must be inferred from the word's phoneme-to-grapheme mapping rather than from a documented borrowing chain. The correct French form is méthotrexate, spelled M-É-T-H-O-T-R-E-X-A-T-E.

Definition

  1. 1
    Antimétabolite utilisé dans le traitement de certaines maladies.

Recorded use

Wiktionary example

These source excerpts show how méthotrexate appears in context. They illustrate usage; the definition above remains the entry’s reference meaning.

  1. Plusieurs études ont montré que des molécules issues de médicaments (divers anticancéreux, tel le méthotrexate, paracétamol, diazépam, parmi d’autres) peuvent passer, malgré les méthodes de purification utilisées, dans le eaux de boisson (...)

Synonyms

améthoptérine

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA). See the methodology for how each field is sourced and updated.

PlainSpell is rendered directly from structured Wiktionary extracts and open word-frequency lists, no number is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of May 6, 2026. Primary sources: Wiktionary (via kaikki.org) and FrequencyWords.

Frequently Asked Questions

How do you spell "méthotrexate"?
"méthotrexate" is spelled M-É-T-H-O-T-R-E-X-A-T-E. The IPA pronunciation is \me.to.tʁak.sat\.
What does "méthotrexate" mean?
As a noun, "méthotrexate" means: Antimétabolite utilisé dans le traitement de certaines maladies.
How do you pronounce "méthotrexate"?
The IPA (International Phonetic Alphabet) transcription for "méthotrexate" is \me.to.tʁak.sat\. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What language does "méthotrexate" come from?
"méthotrexate" is a French word. You can look up definitions, pronunciations, and spelling data for this and other words across English, Spanish, Portuguese, French, and German on PlainSpell.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.
Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list