serotonin

/ˌsɛɹəˈtəʊnɪn/

//ˌsɛɹəˈtəʊnɪn// noun

By · According to Wiktionary data (CC BY-SA) ·

"serotonin" is a 9-letter English headword indexed on PlainSpell.

The verdict

“serotonin” has 13 generated spelling variants in the English index at frequency #20,769. The variants make it a useful spelling check.

#20,769
frequency rank, English
6,566
“S” headwords
13
tracked misspellings

According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - An indoleamine neurotransmitter, 5-hydroxytryptamine, that is involved in depression, appetite, etc., and is crucial in maintaining a sense of well-being, security, etc.

Corpus desk

Index EN-serotonin · serotonin · English

serotonin · rank #20,769 · 13 variants · 0 confusables

  • FREQ-MID #20,769
  • LEN-LONG 9 letters
  • VOW-4 4 vowels
  • CONFUS-0 No pairs
  • VAR-HIGH 13 variants
  • BOOK-DENSE 6,566
  • PHOTO-FINISH serviced

Nearest frequency peer: serviced (+1 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Rank peers near misspelling magnet “serotonin”

Same rarity band: useful when a typo lands on a peer headword

corpus weight

What this shows “serotonin” sits among these FrequencyWords peers; misspelling depth is tracked separately in the edit-distance chart.

Source FrequencyWords open word-frequency list As of September 3, 2026
Key facts for serotonin
PropertyValue
Headwordserotonin
LanguageEnglish
Part of speechNoun
IPA/ˌsɛɹəˈtəʊnɪn/
Letters9
Frequency rank#20,769
Misspellings tracked13
Confusable pairs0
SourceWiktionary (kaikki.org)

Frequency seat of misspelling magnet “serotonin”

This scale runs from the tiny cluster of words that carry ordinary speech (left) to the long tail of words almost nobody reaches for (right).serotoninlands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Same rarity band neighbours include “serviced” (#20,770), “secretive” (#20,767), “shorty” (#20,771). Among 6,566 “S” headwords, “serotonin” is #20,769. Source: FrequencyWords open word-frequency list.

A misspelling magnet

The generator records 13 spelling variants around serotonin (IPA /ˌsɛɹəˈtəʊnɪn/), anoun. Corpus frequency is #20,769 among 6,566 “S” headwords. Dominant gloss: "An indoleamine neurotransmitter, 5-hydroxytryptamine, that is involved in depression, appetite, etc., and is crucial in maintaining a sense of well-being, security, etc.".

Our generated misspelling index lists 13 likely wrong-spelling variants for serotonin, with forms such as "esrotonin", "seortonin", and "serootnin". Each variant is a distinct typo pattern an edit-distance generator flags, typically a doubled-consonant error, a silent-letter drop, or a vowel substitution. This headword has no recorded confusable partner, suggesting its spelling stands apart enough that readers rarely confuse it with something else.

Etymologically, the entry records: From sero- + tone + -in. The correct English form is serotonin, spelled S-E-R-O-T-O-N-I-N.

Definition

  1. 1
    An indoleamine neurotransmitter, 5-hydroxytryptamine, that is involved in depression, appetite, etc., and is crucial in maintaining a sense of well-being, security, etc.

Recorded use

Wiktionary examples

These source excerpts show how serotonin appears in context. They illustrate usage; the definition above remains the entry’s reference meaning.

  1. Notably, mouse lines targeting genes codifying for serotonin receptors, for enzymes involved in 5-HT synthesis as Tph1 and Tph2, in its metabolism as monoaminoxidase A (MAOA) or in its re-uptake as serotonin transporter (SERT), have been generated.
  2. The class of antidepressants most commonly associated with sexual dysfunction is selective serotonin reuptake inhibitors, or SSRIs, which treat depression by ultimately increasing levels of the neurotransmitter serotonin in the brain.

Etymology

From sero- + tone + -in.

Synonyms

5-hydroxytryptamine

This word in other languages

serotonina(Español)sérotonine(Français)Serotonin(Deutsch)serotonina(Português)

Common misspellings

Also misspelled as:

  • esrotonin
  • seortonin
  • serootnin
  • serotnoin
  • serotoinn
  • serotoninn
  • serotonni
  • serotonnin
  • serottonin
  • serrotonin
  • sertoonin
  • sreotonin
  • sserotonin

Misspelling Pattern Breakdown

How far each generated variant is from the correct spelling of serotonin - counted as single-character edits (an insertion, a deletion, or a substituted letter). The larger the bar, the easier the typo is to spot; one-edit slips are the ones that sneak past readers.

esrotonin2seortonin2serootnin2serotnoin2serotoinn2serotoninn1serotonni2serotonnin1
Edit distance from "serotonin"

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "serotonin"?
"serotonin" is spelled S-E-R-O-T-O-N-I-N. The IPA pronunciation is /ˌsɛɹəˈtəʊnɪn/.
What does "serotonin" mean?
As a noun, "serotonin" means: An indoleamine neurotransmitter, 5-hydroxytryptamine, that is involved in depression, appetite, etc., and is crucial in maintaining a sense of well-being, security, etc.
What are common misspellings of "serotonin"?
Common misspellings include "esrotonin", "seortonin", "serootnin", "serotnoin", "serotoinn". The correct spelling is "serotonin".
How do you pronounce "serotonin"?
The IPA (International Phonetic Alphabet) transcription for "serotonin" is /ˌsɛɹəˈtəʊnɪn/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "serotonin"?
From sero- + tone + -in. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "serotonin", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 9 letters (nearest by frequency rank).

secretive#20,767repressed#20,756reforming#20,752recruiter#20,751

Similar misspelling depth

Headwords with a similar count of attested misspellings (13 here; floor ≥5).

starship13 variantsWolfgang13 variantsasparagus13 variantslongitude13 variants

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list