pyrimidine

/paɪˈɹɪ.mɪˌdiːn/

//paɪˈɹɪ.mɪˌdiːn// noun

"pyrimidine" is a 10-letter English headword indexed on PlainSpell.

The verdict

“pyrimidine” is uncommon English (frequency #94,154 among 46,516 “P” headwords), classed as a noun. The kind of spelling people second-guess.

#94,154
frequency rank, English
46,516
“P” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - A diazine in which the two nitrogen atoms are in the meta- positions; it is the basis of three of the bases found in DNA and RNA: thymine, uracil and cytosine

Key facts for pyrimidine
PropertyValue
Headwordpyrimidine
LanguageEnglish
Part of speechNoun
IPA/paɪˈɹɪ.mɪˌdiːn/
Letters10
Frequency rank#94,154
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “pyrimidine” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). pyrimidine lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

pyrimidine is uncommon English at frequency #94,154 among 46,516 “P” headwords, classed as anoun, transcribed /paɪˈɹɪ.mɪˌdiːn/. Rarity is why readers land here mid-draft. Gloss: "A diazine in which the two nitrogen atoms are in the meta- positions; it is the basis of three of the bases found in DNA and RNA: thymine, uracil and cytosine".

No misspelling variants are generated for pyrimidine in our index, since its letter sequence doesn't invite the usual edit-distance slips. This headword has no recorded confusable partner, since nothing in our dataset looks or sounds close enough to cause mix-ups.

Etymologically, the entry records: First attested in 1885. From German Pyrimidin, from German Pyridin (“pyridine”), with the insertion of -mi- from amidine. The correct English form is pyrimidine, spelled P-Y-R-I-M-I-D-I-N-E.

Definition

  1. 1
    A diazine in which the two nitrogen atoms are in the meta- positions; it is the basis of three of the bases found in DNA and RNA: thymine, uracil and cytosine

Etymology

First attested in 1885. From German Pyrimidin, from German Pyridin (“pyridine”), with the insertion of -mi- from amidine.

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "pyrimidine"?
"pyrimidine" is spelled P-Y-R-I-M-I-D-I-N-E. The IPA pronunciation is /paɪˈɹɪ.mɪˌdiːn/.
What does "pyrimidine" mean?
As a noun, "pyrimidine" means: A diazine in which the two nitrogen atoms are in the meta- positions; it is the basis of three of the bases found in DNA and RNA: thymine, uracil and cytosine
How do you pronounce "pyrimidine"?
The IPA (International Phonetic Alphabet) transcription for "pyrimidine" is /paɪˈɹɪ.mɪˌdiːn/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "pyrimidine"?
First attested in 1885. From German Pyrimidin, from German Pyridin (“pyridine”), with the insertion of -mi- from amidine. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “pyrimidine”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is P-Y-R-I-M-I-D-I-N-E - every other letter order is a misspelling in standard orthography.
  • Say it as /paɪˈɹɪ.mɪˌdiːn/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words

Other uncommon English words near this rank

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list FrequencyWords open word-frequency list