opioid
/ˈəʊpiɔɪd/noun
opioid is spelled O-P-I-O-I-D. The wrong spelling people search most is opiod: about 1,120 Bing searches a month in the United States (September 2025 to August 2026), about 4 in 10 of all searches for the word. Opioid is a noun meaning “Any of the natural substances, such as an endorphin, released in the body in response to pain; an endogenous…”. The plural of opioid is opioids.
How do you spell opioid?
Opioid is spelled O-P-I-O-I-D. One wrong spelling is searched or written often enough to measure; together they are about 4 in 10 of the searches for opioid in either form.
Bing searches in the United States: the average month from September 2025 to August 2026 (Microsoft Advertising keyword data through DataForSEO, read September 30, 2026). Wrong spellings are taken from Wiktionary entries tagged "misspelling" and its obsolete or nonstandard forms, Wikipedia's Lists of common misspellings and the codespell dictionary, then measured. The proofreader's marks show the change that corrects each one.
What does opioid mean?
noun
- 1
Any of the natural substances, such as an endorphin, released in the body in response to pain; an endogenous opioid.
- 2
Any of a group of synthetic compounds that exhibit similarities to the opium alkaloids that occur in nature.
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).
How do you pronounce opioid?
- UK /ˈəʊpiɔɪd/
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract). Recordings: LL-Q1860_(eng)-Vealhurl-opioid.wav, Wikimedia Commons (author and licence on each file's page).
Forms of opioid
- opioids plural
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).
How common is opioid?
Opioid appears 2.1 times per million words in written English, the 18,811th most frequent word form in the list.
Source: written frequency: wordfreq 3.1 (a 2021 snapshot of Wikipedia, subtitles, news, books, web text and social media).
Opioid in Spanish, French, German and Portuguese
In the sense substance that has effects similar to opium:
| Language | Words |
|---|---|
| German | Opioid |
| Spanish | opioide |
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract). Translations are Wiktionary's, by sense; a linked word has its own PlainSpell page.
Where does opioid come from?
Attested 1963; from opium + -oid, to distinguish from opiate.
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).