hypercholesterolemia

noun

By · According to Wiktionary data (CC BY-SA) ·

"hypercholesterolemia" is a 20-letter English headword indexed on PlainSpell.

The verdict

“hypercholesterolemia” is uncommon English (frequency #96,072 among 2,646 “H” headwords), classed as a noun. The kind of spelling people second-guess.

#96,072
frequency rank, English
2,646
“H” headwords

According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - An excess of cholesterol in the blood.

Corpus desk

Index EN-hypercholesterolemia · hypercholesterolemia · English

hypercholesterolemia · rank #96,072 · 0 variants · 0 confusables

  • FREQ-RARE #96,072
  • LEN-MEGA 20 letters
  • VOW-9 9 vowels
  • CONFUS-0 No pairs
  • VAR-0 0 variants
  • BOOK-MID 2,646
  • PHOTO-FINISH hurly

Nearest frequency peer: hurly (-2 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Long-tail ranks near “hypercholesterolemia”

Sparse band: bars invert rank so rarer forms read shorter

corpus weight

What this shows Long-tail view: where “hypercholesterolemia” sits against similarly uncommon English ranks.

Source FrequencyWords open word-frequency list As of September 3, 2026
Key facts for hypercholesterolemia
PropertyValue
Headwordhypercholesterolemia
LanguageEnglish
Part of speechNoun
Letters20
Frequency rank#96,072
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Long-tail rank of “hypercholesterolemia” in English

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right).hypercholesterolemiafalls in this rarity band:

#1#100#1K#10K#100K
← used constantlyrarely used →

Ticks step logarithmically, so each one marks a roughly tenfold drop in how often the word turns up. Rare peers in the same band: “hurly” (#96,070), “hurler” (#96,069), “iBook” (#96,075). Among 2,646 “H” headwords, “hypercholesterolemia” is #96,072. Source: FrequencyWords open word-frequency list.

Rare enough to double-check

hypercholesterolemia is uncommon English at frequency #96,072 among 2,646 “H” headwords, classed as anoun. Rarity is why readers land here mid-draft. Gloss: "An excess of cholesterol in the blood.".

hypercholesterolemia has no tracked misspelling variants, since its letter sequence doesn't invite the usual edit-distance slips. We don't track a confusable pairing for this entry, suggesting its spelling stands apart enough that readers rarely confuse it with something else.

Etymologically, the entry records: From hyper- + cholesterol + -emia. The correct English form is hypercholesterolemia, spelled H-Y-P-E-R-C-H-O-L-E-S-T-E-R-O-L-E-M-I-A.

Definition

  1. 1
    An excess of cholesterol in the blood.

Recorded use

Wiktionary example

These source excerpts show how hypercholesterolemia appears in context. They illustrate usage; the definition above remains the entry’s reference meaning.

  1. An inherited predisposition to heart disease, called familial hypercholesterolaemia, results from a rare ‘spelling change’ in the gene for cholesterol receptors.

Etymology

From hyper- + cholesterol + -emia.

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "hypercholesterolemia"?
"hypercholesterolemia" is spelled H-Y-P-E-R-C-H-O-L-E-S-T-E-R-O-L-E-M-I-A.
What does "hypercholesterolemia" mean?
As a noun, "hypercholesterolemia" means: An excess of cholesterol in the blood.
What is the origin of the word "hypercholesterolemia"?
From hyper- + cholesterol + -emia. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "hypercholesterolemia", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 20 letters (nearest by frequency rank).

acetylcholinesterase#96,713tetrahydrocannabinol#94,331phosphatidylinositol#99,701counterrevolutionary#86,169

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list