cytoskeleton

noun

"cytoskeleton" is a 12-letter English headword indexed on PlainSpell.

The verdict

“cytoskeleton” is uncommon English (frequency #66,596 among 43,570 “C” headwords), classed as a noun. The kind of spelling people second-guess.

#66,596
frequency rank, English
43,570
“C” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - A matrix of intercellular protein, in the forms of microfilaments and microtubules, that provide some rigidity to cells

Key facts for cytoskeleton
PropertyValue
Headwordcytoskeleton
LanguageEnglish
Part of speechNoun
Letters12
Frequency rank#66,596
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “cytoskeleton” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). cytoskeleton lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

cytoskeleton is uncommon English at frequency #66,596 among 43,570 “C” headwords, classed as anoun. Rarity is why readers land here mid-draft. Gloss: "A matrix of intercellular protein, in the forms of microfilaments and microtubules, that provide some rigidity to cells".

No misspelling variants are generated for cytoskeleton in our index, since its letter pattern doesn't lend itself to common typo substitutions. No confusable counterpart is on file for this word, which typically means the spelling is too distinctive to be mistaken for another word.

Etymologically, the entry records: From cyto- + skeleton. The correct English form is cytoskeleton, spelled C-Y-T-O-S-K-E-L-E-T-O-N.

Definition

  1. 1
    A matrix of intercellular protein, in the forms of microfilaments and microtubules, that provide some rigidity to cells

Etymology

From cyto- + skeleton.

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "cytoskeleton"?
"cytoskeleton" is spelled C-Y-T-O-S-K-E-L-E-T-O-N.
What does "cytoskeleton" mean?
As a noun, "cytoskeleton" means: A matrix of intercellular protein, in the forms of microfilaments and microtubules, that provide some rigidity to cells
What is the origin of the word "cytoskeleton"?
From cyto- + skeleton. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “cytoskeleton”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is C-Y-T-O-S-K-E-L-E-T-O-N - every other letter order is a misspelling in standard orthography.
  • Browse more English words and confusable pairs in the same reference. English words

Other uncommon English words near this rank

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list