cholinergic

adj

"cholinergic" is a 11-letter English headword indexed on PlainSpell.

The verdict

“cholinergic” is uncommon English (frequency #72,181 among 43,570 “C” headwords), classed as an adjective. The kind of spelling people second-guess.

#72,181
frequency rank, English
43,570
“C” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - Of, pertaining to, activated by, producing or having the same function as acetylcholine.

Key facts for cholinergic
PropertyValue
Headwordcholinergic
LanguageEnglish
Part of speechAdjective
Letters11
Frequency rank#72,181
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “cholinergic” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). cholinergic lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

cholinergic is uncommon English at frequency #72,181 among 43,570 “C” headwords, classed as anadjective. Rarity is why readers land here mid-draft. Gloss: "Of, pertaining to, activated by, producing or having the same function as acetylcholine.".

No misspelling variants are generated for cholinergic in our index, which points to an orthography that plays by predictable English rules. Our dataset records no confusable match here, a sign it's visually distinctive enough not to be mixed up with another word.

Etymologically, the entry records: From choline + -ergic. The correct English form is cholinergic, spelled C-H-O-L-I-N-E-R-G-I-C.

Definition

  1. 1
    Of, pertaining to, activated by, producing or having the same function as acetylcholine.

Etymology

From choline + -ergic.

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "cholinergic"?
"cholinergic" is spelled C-H-O-L-I-N-E-R-G-I-C.
What does "cholinergic" mean?
As an adjective, "cholinergic" means: Of, pertaining to, activated by, producing or having the same function as acetylcholine.
What is the origin of the word "cholinergic"?
From choline + -ergic. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “cholinergic”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is C-H-O-L-I-N-E-R-G-I-C - every other letter order is a misspelling in standard orthography.
  • Browse more English words and confusable pairs in the same reference. English words

Other uncommon English words near this rank

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list