caspase
"caspase" is a 7-letter English headword indexed on PlainSpell.
The verdict
“caspase” is uncommon English (frequency #64,971 among 43,570 “C” headwords), classed as a noun. The kind of spelling people second-guess.
- #64,971
- frequency rank, English
- 43,570
- “C” headwords
According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - Any of several intracellular proteolytic enzymes that mediate apoptosis and pyroptosis.
Corpus desk
Index EN-caspase · caspase · English
caspase · rank #64,971 · 0 variants · 0 confusables
- FREQ-RARE #64,971
- LEN-LONG 7 letters
- VOW-3 3 vowels
- CONFUS-0 No pairs
- VAR-0 0 variants
- BOOK-DENSE 43,570
- PHOTO-FINISH casebook
Nearest frequency peer: casebook (-1 rank slots)
Read with this headword: Spelling guide for this pattern
Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.
Frequency neighbourhood for “caspase”
Lower corpus rank = more everyday usage (inverted bar length for readability)
- Carmona
Carmona
35,033 corpus weight
- Carthaginian
Carthaginian
35,032 corpus weight
- casebook
casebook
35,031 corpus weight
- caspase
caspase
35,030 corpus weight
- centrum
centrum
35,028 corpus weight
- Chaldean
Chaldean
35,027 corpus weight
What this shows Bars show where “caspase” sits against the nearest ranked English headwords in the FrequencyWords band, not a reprint of letter-browse containment.
| Property | Value |
|---|---|
| Headword | caspase |
| Language | English |
| Part of speech | Noun |
| Letters | 7 |
| Frequency rank | #64,971 |
| Misspellings tracked | 0 |
| Confusable pairs | 0 |
| Source | Wiktionary (kaikki.org) |
Where “caspase” sits in English frequency
Rare enough to double-check
caspase is uncommon English at frequency #64,971 among 43,570 “C” headwords, classed as anoun. Rarity is why readers land here mid-draft. Gloss: "Any of several intracellular proteolytic enzymes that mediate apoptosis and pyroptosis.".
Our edit-distance generator produced no likely misspellings for caspase, since its letter sequence doesn't invite the usual edit-distance slips. This entry stands alone in our confusable dataset, since nothing in our dataset looks or sounds close enough to cause mix-ups.
Etymologically, the entry records: Short for cysteine-aspartic acid protease. The correct English form is caspase, spelled C-A-S-P-A-S-E.
Definition
- 1Any of several intracellular proteolytic enzymes that mediate apoptosis and pyroptosis.
Etymology
Short for cysteine-aspartic acid protease.
Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.
PlainSpell is rendered directly from structured Wiktionary extracts and open word-frequency lists, no number is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of May 6, 2026. Primary sources: Wiktionary (via kaikki.org) and FrequencyWords.
Frequently Asked Questions
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Similar English words by spelling shape
Same letter count and similar misspelling depth for "caspase", not the corpus desk frequency band.
Same letter count
Frequency-ranked English headwords with 7 letters (nearest by frequency rank).
Data Source
Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.