antihistamine
/ˌæn.tiˈhɪs.tə.miːn/
"antihistamine" is a 13-letter English headword indexed on PlainSpell.
The verdict
“antihistamine” is uncommon English (frequency #61,958 among 35,202 “A” headwords), classed as a noun. The kind of spelling people second-guess.
- #61,958
- frequency rank, English
- 35,202
- “A” headwords
According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - A drug or substance that counteracts the effects of a histamine. Commonly used to alleviate the symptoms of hay fever and other allergies.
| Property | Value |
|---|---|
| Headword | antihistamine |
| Language | English |
| Part of speech | Noun |
| IPA | /ˌæn.tiˈhɪs.tə.miːn/ |
| Letters | 13 |
| Frequency rank | #61,958 |
| Misspellings tracked | 0 |
| Confusable pairs | 0 |
| Source | Wiktionary (kaikki.org) |
Where “antihistamine” sits in English frequency
Rare enough to double-check
antihistamine is uncommon English at frequency #61,958 among 35,202 “A” headwords, classed as anoun, transcribed /ˌæn.tiˈhɪs.tə.miːn/. Rarity is why readers land here mid-draft. Gloss: "A drug or substance that counteracts the effects of a histamine. Commonly used to alleviate the symptoms of hay fever and other allergies.".
antihistamine doesn't appear in our generated misspelling index, since its letter sequence doesn't invite the usual edit-distance slips. No close-neighbour confusable shows up for this headword in our dataset, a sign it's visually distinctive enough not to be mixed up with another word.
Etymologically, the entry records: From anti- + histamine. The correct English form is antihistamine, spelled A-N-T-I-H-I-S-T-A-M-I-N-E.
Definition
- 1A drug or substance that counteracts the effects of a histamine. Commonly used to alleviate the symptoms of hay fever and other allergies.
Etymology
From anti- + histamine.
Synonyms
This word in other languages
Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.
Frequently Asked Questions
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Using “antihistamine”
The practical upshot for anyone who landed here from a spell-check.
- The one correct English spelling is A-N-T-I-H-I-S-T-A-M-I-N-E - every other letter order is a misspelling in standard orthography.
- Say it as /ˌæn.tiˈhɪs.tə.miːn/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
- Browse more English words and confusable pairs in the same reference. English words
Other uncommon English words near this rank
Data Source
Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.