zygote

/ˈzaɪɡəʊt/

//ˈzaɪɡəʊt// noun

"zygote" is a 6-letter English headword indexed on PlainSpell.

The verdict

“zygote” is uncommon English (frequency #63,393 among 2,810 “Z” headwords), classed as a noun. The kind of spelling people second-guess.

#63,393
frequency rank, English
2,810
“Z” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - A eukaryotic cell formed from the fusion of two gametes (“reproductive cells”) during a fertilization process.

Key facts for zygote
PropertyValue
Headwordzygote
LanguageEnglish
Part of speechNoun
IPA/ˈzaɪɡəʊt/
Letters6
Frequency rank#63,393
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “zygote” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). zygote lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

zygote is uncommon English at frequency #63,393 among 2,810 “Z” headwords, classed as anoun, transcribed /ˈzaɪɡəʊt/. Rarity is why readers land here mid-draft. Gloss: "A eukaryotic cell formed from the fusion of two gametes (“reproductive cells”) during a fertilization process.".

The misspelling generator found no plausible variants for zygote, a sign its spelling follows regular English conventions. We don't track a confusable pairing for this entry, since no other headword is close enough in sound or shape to pair with it.

Etymologically, the entry records: Learned borrowing from Ancient Greek ζῠγωτός (zŭgōtós, “yoked”) + English -ote (suffix meaning ‘having [the thing to which it is attached]’). Ζῠγωτός (Zŭgōtós) is derived from ζῠγόω (zŭgóō, “to join or yoke together”) + -τός (-tós, suffix forming adjectives… The correct English form is zygote, spelled Z-Y-G-O-T-E.

Definition

  1. 1
    A eukaryotic cell formed from the fusion of two gametes (“reproductive cells”) during a fertilization process.

Etymology

Learned borrowing from Ancient Greek ζῠγωτός (zŭgōtós, “yoked”) + English -ote (suffix meaning ‘having [the thing to which it is attached]’). Ζῠγωτός (Zŭgōtós) is derived from ζῠγόω (zŭgóō, “to join or yoke together”) + -τός (-tós, suffix forming adjectives of possibility); and ζῠγόω (zŭgóō) from ζῠγόν (zŭgón, “yoke for joining animals; anything which joins two things together”) (ultimately from Proto-Indo-European *yewg- (“to tie together, join, yoke”)) + -όω (-óō, suffix forming causative or factitive verbs). By surface analysis, zygo- + -ote.

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "zygote"?
"zygote" is spelled Z-Y-G-O-T-E. The IPA pronunciation is /ˈzaɪɡəʊt/.
What does "zygote" mean?
As a noun, "zygote" means: A eukaryotic cell formed from the fusion of two gametes (“reproductive cells”) during a fertilization process.
How do you pronounce "zygote"?
The IPA (International Phonetic Alphabet) transcription for "zygote" is /ˈzaɪɡəʊt/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "zygote"?
Learned borrowing from Ancient Greek ζῠγωτός (zŭgōtós, “yoked”) + English -ote (suffix meaning ‘having [the thing to which it is attached]’). Ζῠγωτός (Zŭgōtós) is derived from ζῠγόω (zŭgóō, “to join or yoke together”) + -τός (-tós, suffix forming ... See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “zygote”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is Z-Y-G-O-T-E - every other letter order is a misspelling in standard orthography.
  • Say it as /ˈzaɪɡəʊt/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words

Other uncommon English words near this rank

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list