vesicle

/ˈvɛsɪkəl/

//ˈvɛsɪkəl// noun

"vesicle" is a 7-letter English headword indexed on PlainSpell.

The verdict

“vesicle” is an uncommon English word, ranked #58,443 in English word frequency and used as a noun.

#58,443
frequency rank, English
7
letters

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - A membrane-bound compartment found in a cell.

Key facts for vesicle
PropertyValue
Headwordvesicle
LanguageEnglish
Part of speechNoun
IPA/ˈvɛsɪkəl/
Letters7
Frequency rank#58,443
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “vesicle” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). vesicle lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Spelling & Dictionary Insight

The English entry for vesicle is 7 letters long, classified as a noun, and transcribed in the International Phonetic Alphabet as /ˈvɛsɪkəl/. Corpus data places it at rank #58,443 in overall English word frequency, marking it as uncommon enough that many writers pause before typing it. Wiktionary records 6 distinct senses for this headword, so context determines which meaning a reader should apply.

Our edit-distance generator produced no likely misspellings for vesicle, suggesting the orthography follows predictable English patterns. This headword has no recorded confusable partner, which typically means the spelling is too distinctive to be mistaken for another word.

Etymologically, the entry records: From Middle French vesicule, from Latin vēsīcula. By surface analysis, vesic- + -le. Doublet of vesicule. The correct English form is vesicle, spelled V-E-S-I-C-L-E.

Definition

  1. 1
    A membrane-bound compartment found in a cell.
  2. 2
    A small bladder-like cell or cavity, as:
  3. 3
    A small bladder-like cell or cavity, as:
  4. 4
    A small bladder-like cell or cavity, as:
  5. 5
    A pocket of embryonic tissue that is the beginning of an organ.
  6. 6
    A small cavity formed in volcanic rock by entrapment of a gas bubble during solidification.

Etymology

From Middle French vesicule, from Latin vēsīcula. By surface analysis, vesic- + -le. Doublet of vesicule.

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "vesicle"?
"vesicle" is spelled V-E-S-I-C-L-E. The IPA pronunciation is /ˈvɛsɪkəl/.
What does "vesicle" mean?
As a noun, "vesicle" means: A membrane-bound compartment found in a cell.
How do you pronounce "vesicle"?
The IPA (International Phonetic Alphabet) transcription for "vesicle" is /ˈvɛsɪkəl/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "vesicle"?
From Middle French vesicule, from Latin vēsīcula. By surface analysis, vesic- + -le. Doublet of vesicule. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “vesicle”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is V-E-S-I-C-L-E - every other letter order is a misspelling in standard orthography.
  • Say it as /ˈvɛsɪkəl/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words
Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list FrequencyWords open word-frequency list