vesicle

/ˈvɛsɪkəl/

//ˈvɛsɪkəl// noun

By · According to Wiktionary data (CC BY-SA) ·

"vesicle" is a 7-letter English headword indexed on PlainSpell.

The verdict

“vesicle” is uncommon English (frequency #58,443 among 969 “V” headwords), classed as a noun. The kind of spelling people second-guess.

#58,443
frequency rank, English
969
“V” headwords

According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - A membrane-bound compartment found in a cell.

Corpus desk

Index EN-vesicle · vesicle · English

vesicle · rank #58,443 · 0 variants · 0 confusables

  • FREQ-RARE #58,443
  • LEN-LONG 7 letters
  • VOW-3 3 vowels
  • CONFUS-0 No pairs
  • VAR-0 0 variants
  • BOOK-MID 969
  • PHOTO-FINISH Venmo

Nearest frequency peer: Venmo (-1 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Long-tail ranks near “vesicle”

Sparse band: bars invert rank so rarer forms read shorter

corpus weight

What this shows Long-tail view: where “vesicle” sits against similarly uncommon English ranks.

Source FrequencyWords open word-frequency list As of September 3, 2026
Key facts for vesicle
PropertyValue
Headwordvesicle
LanguageEnglish
Part of speechNoun
IPA/ˈvɛsɪkəl/
Letters7
Frequency rank#58,443
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Long-tail rank of “vesicle” in English

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right).vesiclefalls in this rarity band:

#1#100#1K#10K#100K
← used constantlyrarely used →

The axis is logarithmic, with each marked tick roughly ten times rarer than the last. Rare peers in the same band: “Venmo” (#58,442), “Velazquez” (#58,441), “Visconti” (#58,447). Among 969 “V” headwords, “vesicle” is #58,443. Source: FrequencyWords open word-frequency list.

Rare enough to double-check

vesicle is uncommon English at frequency #58,443 among 969 “V” headwords, classed as anoun, transcribed /ˈvɛsɪkəl/. Rarity is why readers land here mid-draft. 6 senses are on record.

Our edit-distance generator produced no likely misspellings for vesicle, suggesting the orthography follows predictable English patterns. This headword has no recorded confusable partner, which typically means the spelling is too distinctive to be mistaken for another word.

Etymologically, the entry records: From Middle French vesicule, from Latin vēsīcula. By surface analysis, vesic- + -le. Doublet of vesicule. The correct English form is vesicle, spelled V-E-S-I-C-L-E.

Definition

  1. 1
    A membrane-bound compartment found in a cell.
  2. 2
    A small bladder-like cell or cavity, as:
  3. 3
    A small bladder-like cell or cavity, as:
  4. 4
    A small bladder-like cell or cavity, as:
  5. 5
    A pocket of embryonic tissue that is the beginning of an organ.
  6. 6
    A small cavity formed in volcanic rock by entrapment of a gas bubble during solidification.

Recorded use

Wiktionary example

These source excerpts show how vesicle appears in context. They illustrate usage; the definition above remains the entry’s reference meaning.

  1. It frequently contains holes, or vesicles, especially nearer the surface of a flow where gas has escaped.

Etymology

From Middle French vesicule, from Latin vēsīcula. By surface analysis, vesic- + -le. Doublet of vesicule.

This word in other languages

vesícula(Español)Blase(Deutsch)

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "vesicle"?
"vesicle" is spelled V-E-S-I-C-L-E. The IPA pronunciation is /ˈvɛsɪkəl/.
What does "vesicle" mean?
As a noun, "vesicle" means: A membrane-bound compartment found in a cell.
How do you pronounce "vesicle"?
The IPA (International Phonetic Alphabet) transcription for "vesicle" is /ˈvɛsɪkəl/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "vesicle"?
From Middle French vesicule, from Latin vēsīcula. By surface analysis, vesic- + -le. Doublet of vesicule. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "vesicle", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 7 letters (nearest by frequency rank).

wincing#58,460tremolo#58,423worsted#58,463tigress#58,414

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list