vacuole
/ˈvækjʊˌəʊl/noun
vacuole is a noun meaning “A large membrane-bound vesicle in a cell's cytoplasm” (English Wiktionary, September 2026). It is spelled V-A-C-U-O-L-E, and it appears about once in every 11 million words in written English (wordfreq, 2021 data). The plural of vacuole is vacuoles.
What does vacuole mean?
noun
- 1
A large membrane-bound vesicle in a cell's cytoplasm.
- 2
A small empty or air-filled space or vacuity.
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).
How do you pronounce vacuole?
- /ˈvækjʊˌəʊl/
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract). Recordings: LL-Q1860_(eng)-Vealhurl-vacuole.wav, Wikimedia Commons (author and licence on each file's page).
Forms of vacuole
- vacuoles plural
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).
How common is vacuole?
Vacuole appears about once in every 11 million words in written English, the 101,613th most frequent word form in the list.
Source: written frequency: wordfreq 3.1 (a 2021 snapshot of Wikipedia, subtitles, news, books, web text and social media).
Vacuole in Spanish, French, German and Portuguese
In the sense large membrane-bound vesicle:
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract). Translations are Wiktionary's, by sense; a linked word has its own PlainSpell page.
Where does vacuole come from?
From French vacuole, from Medieval Latin vacuola, formed as a diminutive of Latin vacuus (“empty”).
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).