trypsin
/ˈtɹɪp.sɪn/
"trypsin" is a 7-letter English headword indexed on PlainSpell.
The verdict
“trypsin” is uncommon English (frequency #77,297 among 3,151 “T” headwords), classed as a noun. The kind of spelling people second-guess.
- #77,297
- frequency rank, English
- 3,151
- “T” headwords
According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - A digestive enzyme that cleaves peptide bonds (a serine protease)
Corpus desk
Index EN-trypsin · trypsin · English
trypsin · rank #77,297 · 0 variants · 0 confusables
- FREQ-RARE #77,297
- LEN-LONG 7 letters
- VOW-2 2 vowels
- CONFUS-0 No pairs
- VAR-0 0 variants
- BOOK-MID 3,151
- PHOTO-FINISH trow
Nearest frequency peer: trow (-2 rank slots)
Read with this headword: Spelling guide for this pattern
Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.
Long-tail ranks near “trypsin”
Sparse band: bars invert rank so rarer forms read shorter
- transexual
transexual
22,710 corpus weight
- transworld
transworld
22,709 corpus weight
- treeless
treeless
22,708 corpus weight
- tripwire
tripwire
22,707 corpus weight
- trow
trow
22,706 corpus weight
- trypsin
trypsin
22,704 corpus weight
What this shows Long-tail view: where “trypsin” sits against similarly uncommon English ranks.
| Property | Value |
|---|---|
| Headword | trypsin |
| Language | English |
| Part of speech | Noun |
| IPA | /ˈtɹɪp.sɪn/ |
| Letters | 7 |
| Frequency rank | #77,297 |
| Misspellings tracked | 0 |
| Confusable pairs | 0 |
| Source | Wiktionary (kaikki.org) |
Long-tail rank of “trypsin” in English
Rare enough to double-check
trypsin is uncommon English at frequency #77,297 among 3,151 “T” headwords, classed as anoun, transcribed /ˈtɹɪp.sɪn/. Rarity is why readers land here mid-draft. Gloss: "A digestive enzyme that cleaves peptide bonds (a serine protease)".
trypsin doesn't appear in our generated misspelling index, suggesting the orthography follows predictable English patterns. We don't track a confusable pairing for this entry, a sign it's visually distinctive enough not to be mixed up with another word.
Etymologically, the entry records: From Ancient Greek τρῖψις (trîpsis, “rubbing”) + -in, since the substance was first found on rubbing down the pancreas with glycerine. The correct English form is trypsin, spelled T-R-Y-P-S-I-N.
Definition
- 1A digestive enzyme that cleaves peptide bonds (a serine protease)
Etymology
From Ancient Greek τρῖψις (trîpsis, “rubbing”) + -in, since the substance was first found on rubbing down the pancreas with glycerine.
This word in other languages
Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.
Frequently Asked Questions
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Similar English words by spelling shape
Same letter count and similar misspelling depth for "trypsin", not the corpus desk frequency band.
Same letter count
Frequency-ranked English headwords with 7 letters (nearest by frequency rank).