spironolactone
/ˌspʌɪ.ɹən.ə(ʊ)ˈlæk.təʊn/
"spironolactone" is a 14-letter English headword indexed on PlainSpell.
The verdict
“spironolactone” is uncommon English (frequency #75,438 among 6,566 “S” headwords), classed as a noun. The kind of spelling people second-guess.
- #75,438
- frequency rank, English
- 6,566
- “S” headwords
According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - A steroid drug which acts as an antimineralocorticoid (for which purpose it is used in the treatment of certain types of edema and hypertension) and an antiandrogen (for which purpose it is used as...
Corpus desk
Index EN-spironolactone · spironolactone · English
spironolactone · rank #75,438 · 0 variants · 0 confusables
- FREQ-RARE #75,438
- LEN-MEGA 14 letters
- VOW-6 6 vowels
- CONFUS-0 No pairs
- VAR-0 0 variants
- BOOK-DENSE 6,566
- PHOTO-FINISH specular
Nearest frequency peer: specular (-2 rank slots)
Read with this headword: Spelling guide for this pattern
Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.
Long-tail ranks near “spironolactone”
Sparse band: bars invert rank so rarer forms read shorter
- Somoza
Somoza
24,570 corpus weight
- soothsayer
soothsayer
24,569 corpus weight
- spasticity
spasticity
24,567 corpus weight
- specular
specular
24,565 corpus weight
- spironolact…
spironolactone
24,563 corpus weight
- squeegee
squeegee
24,559 corpus weight
What this shows Long-tail view: where “spironolactone” sits against similarly uncommon English ranks.
| Property | Value |
|---|---|
| Headword | spironolactone |
| Language | English |
| Part of speech | Noun |
| IPA | /ˌspʌɪ.ɹən.ə(ʊ)ˈlæk.təʊn/ |
| Letters | 14 |
| Frequency rank | #75,438 |
| Misspellings tracked | 0 |
| Confusable pairs | 0 |
| Source | Wiktionary (kaikki.org) |
Long-tail rank of “spironolactone” in English
Rare enough to double-check
spironolactone is uncommon English at frequency #75,438 among 6,566 “S” headwords, classed as anoun, transcribed /ˌspʌɪ.ɹən.ə(ʊ)ˈlæk.təʊn/. Rarity is why readers land here mid-draft. Gloss: "A steroid drug which acts as an antimineralocorticoid (for which purpose it is used in the treatment of certain types of edema and hypertension) and an antiandrogen (for which purpose it is used as...".
No generated misspelling entries exist for spironolactone in our index, and the word's spelling is regular enough that our generator found nothing worth flagging. No confusable counterpart is on file for this word, since nothing in our dataset looks or sounds close enough to cause mix-ups.
Etymologically, the entry records: From spiro + -one + -o- + lactone. The correct English form is spironolactone, spelled S-P-I-R-O-N-O-L-A-C-T-O-N-E.
Definition
- 1A steroid drug which acts as an antimineralocorticoid (for which purpose it is used in the treatment of certain types of edema and hypertension) and an antiandrogen (for which purpose it is used as part of some types of hormone therapy, especially for transgender women).
Etymology
From spiro + -one + -o- + lactone.
Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.
Frequently Asked Questions
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Similar English words by spelling shape
Same letter count and similar misspelling depth for "spironolactone", not the corpus desk frequency band.
Same letter count
Frequency-ranked English headwords with 14 letters (nearest by frequency rank).