sildenafil

/sɪlˈdɛn.ə.fɪl/

//sɪlˈdɛn.ə.fɪl// noun

"sildenafil" is a 10-letter English headword indexed on PlainSpell.

The verdict

“sildenafil” is uncommon English (frequency #87,827 among 54,294 “S” headwords), classed as a noun. The kind of spelling people second-guess.

#87,827
frequency rank, English
54,294
“S” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effe...

Corpus desk

Index EN-sildenafil · sildenafil · English

sildenafil · rank #87,827 · 0 variants · 0 confusables

  • FREQ-RARE #87,827
  • LEN-MEGA 10 letters
  • VOW-4 4 vowels
  • CONFUS-0 No pairs
  • VAR-0 0 variants
  • BOOK-DENSE 54,294
  • PHOTO-FINISH silverfish

Nearest frequency peer: silverfish (+2 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Frequency neighbourhood for “sildenafil”

Lower corpus rank = more everyday usage (inverted bar length for readability)

corpus weight

What this shows Bars show where “sildenafil” sits against the nearest ranked English headwords in the FrequencyWords band, not a reprint of letter-browse containment.

Source FrequencyWords open word-frequency list As of May 6, 2026
Key facts for sildenafil
PropertyValue
Headwordsildenafil
LanguageEnglish
Part of speechNoun
IPA/sɪlˈdɛn.ə.fɪl/
Letters10
Frequency rank#87,827
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “sildenafil” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). sildenafil lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

sildenafil is uncommon English at frequency #87,827 among 54,294 “S” headwords, classed as anoun, transcribed /sɪlˈdɛn.ə.fɪl/. Rarity is why readers land here mid-draft. Gloss: "A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effe...".

No misspelling variants are generated for sildenafil in our index, a straightforward case of a spelling with little room for common typos. We don't track a confusable pairing for this entry, since its spelling is unusual enough that it doesn't cluster with a lookalike.

Etymologically, the entry records: Probably from s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl. The correct English form is sildenafil, spelled S-I-L-D-E-N-A-F-I-L.

Definition

  1. 1
    A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra.

Etymology

Probably from s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl.

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

PlainSpell is rendered directly from structured Wiktionary extracts and open word-frequency lists, no number is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of May 6, 2026. Primary sources: Wiktionary (via kaikki.org) and FrequencyWords.

Frequently Asked Questions

How do you spell "sildenafil"?
"sildenafil" is spelled S-I-L-D-E-N-A-F-I-L. The IPA pronunciation is /sɪlˈdɛn.ə.fɪl/.
What does "sildenafil" mean?
As a noun, "sildenafil" means: A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effe...
How do you pronounce "sildenafil"?
The IPA (International Phonetic Alphabet) transcription for "sildenafil" is /sɪlˈdɛn.ə.fɪl/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "sildenafil"?
Probably from s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "sildenafil", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 10 letters (nearest by frequency rank).

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list