sertraline

/ˈsɜː.tɹəˌliːn/

//ˈsɜː.tɹəˌliːn// noun

"sertraline" is a 10-letter English headword indexed on PlainSpell.

The verdict

“sertraline” is uncommon English (frequency #80,867 among 6,566 “S” headwords), classed as a noun. The kind of spelling people second-guess.

#80,867
frequency rank, English
6,566
“S” headwords

According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - An antidepressant drug C₁₇H₁₇NCl₂ administered in the form of its hydrochloride and acting to enhance serotonin activity.

Corpus desk

Index EN-sertraline · sertraline · English

sertraline · rank #80,867 · 0 variants · 0 confusables

  • FREQ-RARE #80,867
  • LEN-MEGA 10 letters
  • VOW-4 4 vowels
  • CONFUS-0 No pairs
  • VAR-0 0 variants
  • BOOK-DENSE 6,566
  • PHOTO-FINISH seinen

Nearest frequency peer: seinen (-5 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Long-tail ranks near “sertraline”

Sparse band: bars invert rank so rarer forms read shorter

corpus weight

What this shows Long-tail view: where “sertraline” sits against similarly uncommon English ranks.

Source FrequencyWords open word-frequency list As of September 3, 2026
Key facts for sertraline
PropertyValue
Headwordsertraline
LanguageEnglish
Part of speechNoun
IPA/ˈsɜː.tɹəˌliːn/
Letters10
Frequency rank#80,867
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Long-tail rank of “sertraline” in English

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right).sertralinefalls in this rarity band:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Rare peers in the same band: “seinen” (#80,862), “shd” (#80,873), “Shepperton” (#80,874). Among 6,566 “S” headwords, “sertraline” is #80,867. Source: FrequencyWords open word-frequency list.

Rare enough to double-check

sertraline is uncommon English at frequency #80,867 among 6,566 “S” headwords, classed as anoun, transcribed /ˈsɜː.tɹəˌliːn/. Rarity is why readers land here mid-draft. Gloss: "An antidepressant drug C₁₇H₁₇NCl₂ administered in the form of its hydrochloride and acting to enhance serotonin activity.".

sertraline has no tracked misspelling variants, since its letter sequence doesn't invite the usual edit-distance slips. No confusable counterpart is on file for this word, since no other headword is close enough in sound or shape to pair with it.

Etymologically, the entry records: From ser(otonin) + -traline (“serotonin reuptake inhibitor”). The correct English form is sertraline, spelled S-E-R-T-R-A-L-I-N-E.

Definition

  1. 1
    An antidepressant drug C₁₇H₁₇NCl₂ administered in the form of its hydrochloride and acting to enhance serotonin activity.

Etymology

From ser(otonin) + -traline (“serotonin reuptake inhibitor”).

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "sertraline"?
"sertraline" is spelled S-E-R-T-R-A-L-I-N-E. The IPA pronunciation is /ˈsɜː.tɹəˌliːn/.
What does "sertraline" mean?
As a noun, "sertraline" means: An antidepressant drug C₁₇H₁₇NCl₂ administered in the form of its hydrochloride and acting to enhance serotonin activity.
How do you pronounce "sertraline"?
The IPA (International Phonetic Alphabet) transcription for "sertraline" is /ˈsɜː.tɹəˌliːn/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "sertraline"?
From ser(otonin) + -traline (“serotonin reuptake inhibitor”). See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "sertraline", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 10 letters (nearest by frequency rank).

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list