renin
/ˈɹiː.nɪn/
"renin" is a 5-letter English headword indexed on PlainSpell.
The verdict
“renin” is uncommon English (frequency #85,700 among 21,470 “R” headwords), classed as a noun. The kind of spelling people second-guess.
- #85,700
- frequency rank, English
- 21,470
- “R” headwords
According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - A circulating enzyme released by mammalian kidneys that converts angiotensinogen to angiotensin I. Due to its activity which ultimately leads to the formation of angiotensin II and aldosterone, thi...
| Property | Value |
|---|---|
| Headword | renin |
| Language | English |
| Part of speech | Noun |
| IPA | /ˈɹiː.nɪn/ |
| Letters | 5 |
| Frequency rank | #85,700 |
| Misspellings tracked | 0 |
| Confusable pairs | 0 |
| Source | Wiktionary (kaikki.org) |
Where “renin” sits in English frequency
Rare enough to double-check
renin is uncommon English at frequency #85,700 among 21,470 “R” headwords, classed as anoun, transcribed /ˈɹiː.nɪn/. Rarity is why readers land here mid-draft. Gloss: "A circulating enzyme released by mammalian kidneys that converts angiotensinogen to angiotensin I. Due to its activity which ultimately leads to the formation of angiotensin II and aldosterone, thi...".
Our edit-distance generator produced no likely misspellings for renin, which points to an orthography that plays by predictable English rules. This entry stands alone in our confusable dataset, which tends to mean the word is visually distinctive enough to stand on its own.
Etymologically, the entry records: From reno- + -in. The correct English form is renin, spelled R-E-N-I-N.
Definition
- 1A circulating enzyme released by mammalian kidneys that converts angiotensinogen to angiotensin I. Due to its activity which ultimately leads to the formation of angiotensin II and aldosterone, this hormone plays a role in maintaining blood pressure.
Etymology
From reno- + -in.
Synonyms
Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.
Frequently Asked Questions
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Using “renin”
The practical upshot for anyone who landed here from a spell-check.
- The one correct English spelling is R-E-N-I-N - every other letter order is a misspelling in standard orthography.
- Say it as /ˈɹiː.nɪn/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
- Browse more English words and confusable pairs in the same reference. English words
Other uncommon English words near this rank
Data Source
Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.