quinine

/kwɪˈniːn/

//kwɪˈniːn// noun

"quinine" is a 7-letter English headword indexed on PlainSpell.

The verdict

“quinine” is uncommon English (frequency #51,340 among 2,880 “Q” headwords), classed as a noun. The kind of spelling people second-guess.

#51,340
frequency rank, English
2,880
“Q” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - An alkaloid with the chemical formula C₂₀H₂₄N₂O₂, originally derived from cinchona bark (from plants of the genus Cinchona), used to treat malaria and as an ingredient of tonic water, which present...

Key facts for quinine
PropertyValue
Headwordquinine
LanguageEnglish
Part of speechNoun
IPA/kwɪˈniːn/
Letters7
Frequency rank#51,340
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “quinine” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). quinine lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

quinine is uncommon English at frequency #51,340 among 2,880 “Q” headwords, classed as anoun, transcribed /kwɪˈniːn/. Rarity is why readers land here mid-draft. Gloss: "An alkaloid with the chemical formula C₂₀H₂₄N₂O₂, originally derived from cinchona bark (from plants of the genus Cinchona), used to treat malaria and as an ingredient of tonic water, which present...".

No misspelling variants are generated for quinine in our index, and the word's spelling is regular enough that our generator found nothing worth flagging. It is not paired with a close-neighbour confusable in our dataset, suggesting its spelling stands apart enough that readers rarely confuse it with something else.

Etymologically, the entry records: The noun is either: * derived from Spanish quina (“quinine”) (a clipping of quinaquina (“Cinchona bark”)) + English -ine (suffix forming names of chemical substances, especially (among others) alkaloidal substances); or * borrowed from French quinine, from … The correct English form is quinine, spelled Q-U-I-N-I-N-E.

Definition

  1. 1
    An alkaloid with the chemical formula C₂₀H₂₄N₂O₂, originally derived from cinchona bark (from plants of the genus Cinchona), used to treat malaria and as an ingredient of tonic water, which presents as a bitter colourless powder; also, a drug containing quinine or a chemical compound derived from it.

Etymology

The noun is either: * derived from Spanish quina (“quinine”) (a clipping of quinaquina (“Cinchona bark”)) + English -ine (suffix forming names of chemical substances, especially (among others) alkaloidal substances); or * borrowed from French quinine, from quin(quina) (“Cinchona bark”) + -ine (feminine form of -in (suffix forming nouns)). Spanish quinaquina and French quinquina are both derived from Quechua kina-kina, a reduplication of kina (“bark; (specifically) Cinchona bark”). The verb is derived from the noun.

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "quinine"?
"quinine" is spelled Q-U-I-N-I-N-E. The IPA pronunciation is /kwɪˈniːn/.
What does "quinine" mean?
As a noun, "quinine" means: An alkaloid with the chemical formula C₂₀H₂₄N₂O₂, originally derived from cinchona bark (from plants of the genus Cinchona), used to treat malaria and as an ingredient of tonic water, which present...
How do you pronounce "quinine"?
The IPA (International Phonetic Alphabet) transcription for "quinine" is /kwɪˈniːn/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "quinine"?
The noun is either: * derived from Spanish quina (“quinine”) (a clipping of quinaquina (“Cinchona bark”)) + English -ine (suffix forming names of chemical substances, especially (among others) alkaloidal substances); or * borrowed from French quin... See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “quinine”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is Q-U-I-N-I-N-E - every other letter order is a misspelling in standard orthography.
  • Say it as /kwɪˈniːn/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words

Other uncommon English words near this rank

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list FrequencyWords open word-frequency list