promethazine

/pɹə(ʊ)ˈmɛθ.ə.ziːn/

//pɹə(ʊ)ˈmɛθ.ə.ziːn// noun

"promethazine" is a 12-letter English headword indexed on PlainSpell.

The verdict

“promethazine” is uncommon English (frequency #94,146 among 4,417 “P” headwords), classed as a noun. The kind of spelling people second-guess.

#94,146
frequency rank, English
4,417
“P” headwords

According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - A first-generation H₁ receptor antagonist derived from phenothiazine, used as antihistamine and antiemetic medication with strong sedative effects.

Corpus desk

Index EN-promethazine · promethazine · English

promethazine · rank #94,146 · 0 variants · 0 confusables

  • FREQ-RARE #94,146
  • LEN-MEGA 12 letters
  • VOW-5 5 vowels
  • CONFUS-0 No pairs
  • VAR-0 0 variants
  • BOOK-MID 4,417
  • PHOTO-FINISH pretest

Nearest frequency peer: pretest (-1 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Long-tail ranks near “promethazine”

Sparse band: bars invert rank so rarer forms read shorter

corpus weight

What this shows Long-tail view: where “promethazine” sits against similarly uncommon English ranks.

Source FrequencyWords open word-frequency list As of September 3, 2026
Key facts for promethazine
PropertyValue
Headwordpromethazine
LanguageEnglish
Part of speechNoun
IPA/pɹə(ʊ)ˈmɛθ.ə.ziːn/
Letters12
Frequency rank#94,146
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Long-tail rank of “promethazine” in English

This scale runs from the tiny cluster of words that carry ordinary speech (left) to the long tail of words almost nobody reaches for (right).promethazinefalls in this rarity band:

#1#100#1K#10K#100K
← used constantlyrarely used →

The axis is logarithmic, with each marked tick roughly ten times rarer than the last. Rare peers in the same band: “pretest” (#94,145), “propagandistic” (#94,147), “Prestwich” (#94,144). Among 4,417 “P” headwords, “promethazine” is #94,146. Source: FrequencyWords open word-frequency list.

Rare enough to double-check

promethazine is uncommon English at frequency #94,146 among 4,417 “P” headwords, classed as anoun, transcribed /pɹə(ʊ)ˈmɛθ.ə.ziːn/. Rarity is why readers land here mid-draft. Gloss: "A first-generation H₁ receptor antagonist derived from phenothiazine, used as antihistamine and antiemetic medication with strong sedative effects.".

The misspelling generator found no plausible variants for promethazine, a sign its spelling follows regular English conventions. No confusable counterpart is on file for this word, suggesting its spelling stands apart enough that readers rarely confuse it with something else.

Etymologically, the entry records: From pro(p)- + meth- + (phenothi)azine. The correct English form is promethazine, spelled P-R-O-M-E-T-H-A-Z-I-N-E.

Definition

  1. 1
    A first-generation H₁ receptor antagonist derived from phenothiazine, used as antihistamine and antiemetic medication with strong sedative effects.

Recorded use

Wiktionary example

These source excerpts show how promethazine appears in context. They illustrate usage; the definition above remains the entry’s reference meaning.

  1. For quotations using this term, see Citations:promethazine.

Etymology

From pro(p)- + meth- + (phenothi)azine.

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "promethazine"?
"promethazine" is spelled P-R-O-M-E-T-H-A-Z-I-N-E. The IPA pronunciation is /pɹə(ʊ)ˈmɛθ.ə.ziːn/.
What does "promethazine" mean?
As a noun, "promethazine" means: A first-generation H₁ receptor antagonist derived from phenothiazine, used as antihistamine and antiemetic medication with strong sedative effects.
How do you pronounce "promethazine"?
The IPA (International Phonetic Alphabet) transcription for "promethazine" is /pɹə(ʊ)ˈmɛθ.ə.ziːn/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "promethazine"?
From pro(p)- + meth- + (phenothi)azine. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "promethazine", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 12 letters (nearest by frequency rank).

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list