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prodrug

/ˈpɹoʊ.dɹʌɡ/noun, adjective

prodrug is a noun meaning “A drug that is administered in an inactive form that is metabolised in the body into a biologically active compound” (English Wiktionary, September 2026). It is spelled P-R-O-D-R-U-G and has 2 syllables, and it appears about once in every 15 million words in written English (wordfreq, 2021 data). The plural of prodrug is prodrugs.

What does prodrug mean?

noun

  1. 1

    A drug that is administered in an inactive form that is metabolised in the body into a biologically active compound.

adjective

  1. 1

    In favour of recreational drugs.

Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).

How do you pronounce prodrug?

  • UK /ˈpɹəʊ.dɹʌɡ/
  • US /ˈpɹoʊ.dɹʌɡ/

As an adjective (“In favour of recreational drugs”): /pɹəʊˈdɹʌɡ/, /pɹoʊˈdɹʌɡ/.

Prodrug has 2 syllables (counted from the pronunciation).

Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).

Forms of prodrug

  • prodrugs plural
  • more prodrug comparative
  • most prodrug superlative

Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).

How common is prodrug?

Prodrug appears about once in every 15 million words in written English, the 117,098th most frequent word form in the list.

Source: written frequency: wordfreq 3.1 (a 2021 snapshot of Wikipedia, subtitles, news, books, web text and social media).

Where does prodrug come from?

From pro- (“substitute for”) + drug.

Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).