prednisolone

/pɹɛdˈnɪs.ə.ləʊn/

//pɹɛdˈnɪs.ə.ləʊn// noun

"prednisolone" is a 12-letter English headword indexed on PlainSpell.

The verdict

“prednisolone” is uncommon English (frequency #81,716 among 46,516 “P” headwords), classed as a noun. The kind of spelling people second-guess.

#81,716
frequency rank, English
46,516
“P” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - A synthetic glucocorticoid C₂₁H₂₈O₅ that is a dehydrogenated analog of cortisol and is used especially as an anti-inflammatory drug.

Key facts for prednisolone
PropertyValue
Headwordprednisolone
LanguageEnglish
Part of speechNoun
IPA/pɹɛdˈnɪs.ə.ləʊn/
Letters12
Frequency rank#81,716
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “prednisolone” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). prednisolone lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

prednisolone is uncommon English at frequency #81,716 among 46,516 “P” headwords, classed as anoun, transcribed /pɹɛdˈnɪs.ə.ləʊn/. Rarity is why readers land here mid-draft. Gloss: "A synthetic glucocorticoid C₂₁H₂₈O₅ that is a dehydrogenated analog of cortisol and is used especially as an anti-inflammatory drug.".

prednisolone has no tracked misspelling variants, since its letter sequence doesn't invite the usual edit-distance slips. It is not paired with a close-neighbour confusable in our dataset, since its spelling is unusual enough that it doesn't cluster with a lookalike.

Etymologically, the entry records: From prednis(-ol)one. The correct English form is prednisolone, spelled P-R-E-D-N-I-S-O-L-O-N-E.

Definition

  1. 1
    A synthetic glucocorticoid C₂₁H₂₈O₅ that is a dehydrogenated analog of cortisol and is used especially as an anti-inflammatory drug.

Etymology

From prednis(-ol)one.

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "prednisolone"?
"prednisolone" is spelled P-R-E-D-N-I-S-O-L-O-N-E. The IPA pronunciation is /pɹɛdˈnɪs.ə.ləʊn/.
What does "prednisolone" mean?
As a noun, "prednisolone" means: A synthetic glucocorticoid C₂₁H₂₈O₅ that is a dehydrogenated analog of cortisol and is used especially as an anti-inflammatory drug.
How do you pronounce "prednisolone"?
The IPA (International Phonetic Alphabet) transcription for "prednisolone" is /pɹɛdˈnɪs.ə.ləʊn/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "prednisolone"?
From prednis(-ol)one. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “prednisolone”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is P-R-E-D-N-I-S-O-L-O-N-E - every other letter order is a misspelling in standard orthography.
  • Say it as /pɹɛdˈnɪs.ə.ləʊn/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words

Other uncommon English words near this rank

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list FrequencyWords open word-frequency list