polypeptide

noun

By · According to Wiktionary data (CC BY-SA) ·

"polypeptide" is a 11-letter English headword indexed on PlainSpell.

The verdict

“polypeptide” has 17 generated spelling variants in the English index at frequency #47,268. The variants make it a useful spelling check.

#47,268
frequency rank, English
4,417
“P” headwords
17
tracked misspellings

According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - Any polymer of (same or different) amino acids joined via peptide bonds.

Corpus desk

Index EN-polypeptide · polypeptide · English

polypeptide · rank #47,268 · 17 variants · 0 confusables

  • FREQ-MID #47,268
  • LEN-MEGA 11 letters
  • VOW-5 5 vowels
  • CONFUS-0 No pairs
  • VAR-HIGH 17 variants
  • BOOK-MID 4,417
  • PHOTO-FINISH postulate

Nearest frequency peer: postulate (+1 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Rank peers near misspelling magnet “polypeptide”

Same rarity band: useful when a typo lands on a peer headword

corpus weight

What this shows “polypeptide” sits among these FrequencyWords peers; misspelling depth is tracked separately in the edit-distance chart.

Source FrequencyWords open word-frequency list As of September 3, 2026
Key facts for polypeptide
PropertyValue
Headwordpolypeptide
LanguageEnglish
Part of speechNoun
Letters11
Frequency rank#47,268
Misspellings tracked17
Confusable pairs0
SourceWiktionary (kaikki.org)

Frequency seat of misspelling magnet “polypeptide”

This scale runs from the tiny cluster of words that carry ordinary speech (left) to the long tail of words almost nobody reaches for (right).polypeptidelands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Ticks step logarithmically, so each one marks a roughly tenfold drop in how often the word turns up. Same rarity band neighbours include “postulate” (#47,269), “PMC” (#47,266), “presidio” (#47,270). Among 4,417 “P” headwords, “polypeptide” is #47,268. Source: FrequencyWords open word-frequency list.

A misspelling magnet

The generator records 17 spelling variants around polypeptide, anoun. Corpus frequency is #47,268 among 4,417 “P” headwords. Wiktionary lists 3 senses, so context still picks the gloss.

Our generated misspelling index lists 17 likely wrong-spelling variants for polypeptide, with forms such as "oplypeptide", "ploypeptide", and "pollypeptide". Each of these forms differs from the correct spelling by one small edit: a doubled letter, a dropped silent letter, or a substituted vowel. We don't track a confusable pairing for this entry, which tends to mean the word is visually distinctive enough to stand on its own.

Etymologically, the entry records: From poly- + peptide. The correct English form is polypeptide, spelled P-O-L-Y-P-E-P-T-I-D-E.

Definition

  1. 1
    Any polymer of (same or different) amino acids joined via peptide bonds.
  2. 2
    Any such polymer that is not folded into a secondary structure of a protein.
  3. 3
    A small protein containing up to 100 amino acids; see also oligopeptide.

Etymology

From poly- + peptide.

This word in other languages

polypeptide(Français)

Common misspellings

Also misspelled as:

  • oplypeptide
  • ploypeptide
  • pollypeptide
  • polpyeptide
  • polyepptide
  • polypepitde
  • polypepptide
  • polypeptdie
  • polypeptidde
  • polypeptied
  • polypepttide
  • polypetpide
  • polyppeptide
  • polyppetide
  • polyypeptide
  • poylpeptide
  • ppolypeptide

Misspelling Pattern Breakdown

How far each generated variant is from the correct spelling of polypeptide - expressed in single-character edits (insert, delete, or swap one letter). Bigger bars stand out at a glance; a one-edit slip is the hardest to catch.

oplypeptide2ploypeptide2pollypeptide1polpyeptide2polyepptide2polypepitde2polypepptide1polypeptdie2
Edit distance from "polypeptide"

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "polypeptide"?
"polypeptide" is spelled P-O-L-Y-P-E-P-T-I-D-E.
What does "polypeptide" mean?
As a noun, "polypeptide" means: Any polymer of (same or different) amino acids joined via peptide bonds.
What are common misspellings of "polypeptide"?
Common misspellings include "oplypeptide", "ploypeptide", "pollypeptide", "polpyeptide", "polyepptide". The correct spelling is "polypeptide".
What is the origin of the word "polypeptide"?
From poly- + peptide. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "polypeptide", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 11 letters (nearest by frequency rank).

phosphatase#47,255rationalism#47,287Rittenhouse#47,309sociopathic#47,342

Similar misspelling depth

Headwords with a similar count of attested misspellings (17 here; floor ≥5).

multichannel17 variantsmechanistic17 variantsmalfeasance17 variantsunionization17 variants

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list