nicotinamide

noun

"nicotinamide" is a 12-letter English headword indexed on PlainSpell.

The verdict

“nicotinamide” is uncommon English (frequency #91,857 among 24,391 “N” headwords), classed as a noun. The kind of spelling people second-guess.

#91,857
frequency rank, English
24,391
“N” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - The amide of nicotinic acid (or niacin).

Key facts for nicotinamide
PropertyValue
Headwordnicotinamide
LanguageEnglish
Part of speechNoun
Letters12
Frequency rank#91,857
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “nicotinamide” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). nicotinamide lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

nicotinamide is uncommon English at frequency #91,857 among 24,391 “N” headwords, classed as anoun. Rarity is why readers land here mid-draft. Gloss: "The amide of nicotinic acid (or niacin).".

We couldn't generate a plausible misspelling set for nicotinamide, a sign its spelling follows regular English conventions. No confusable counterpart is on file for this word, since its spelling is unusual enough that it doesn't cluster with a lookalike.

Etymologically, the entry records: Blend of nicotine + amide, equivalent to nicotine + -amide. The correct English form is nicotinamide, spelled N-I-C-O-T-I-N-A-M-I-D-E.

Definition

  1. 1
    The amide of nicotinic acid (or niacin).

Etymology

Blend of nicotine + amide, equivalent to nicotine + -amide.

Synonyms

E375niacinamidenicotinic acid amide

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "nicotinamide"?
"nicotinamide" is spelled N-I-C-O-T-I-N-A-M-I-D-E.
What does "nicotinamide" mean?
As a noun, "nicotinamide" means: The amide of nicotinic acid (or niacin).
What is the origin of the word "nicotinamide"?
Blend of nicotine + amide, equivalent to nicotine + -amide. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “nicotinamide”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is N-I-C-O-T-I-N-A-M-I-D-E - every other letter order is a misspelling in standard orthography.
  • Browse more English words and confusable pairs in the same reference. English words

Other uncommon English words near this rank

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list