niacin

/ˈnaɪəsɪn/

//ˈnaɪəsɪn// noun

"niacin" is a 6-letter English headword indexed on PlainSpell.

The verdict

“niacin” is uncommon English (frequency #52,519 among 24,391 “N” headwords), classed as a noun. The kind of spelling people second-guess.

#52,519
frequency rank, English
24,391
“N” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - A water-soluble vitamin, a component of vitamin B complex, found in meat, yeast, and dairy products; it is essential to metabolism.

Key facts for niacin
PropertyValue
Headwordniacin
LanguageEnglish
Part of speechNoun
IPA/ˈnaɪəsɪn/
Letters6
Frequency rank#52,519
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “niacin” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). niacin lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

niacin is uncommon English at frequency #52,519 among 24,391 “N” headwords, classed as anoun, transcribed /ˈnaɪəsɪn/. Rarity is why readers land here mid-draft. Gloss: "A water-soluble vitamin, a component of vitamin B complex, found in meat, yeast, and dairy products; it is essential to metabolism.".

Our edit-distance generator produced no likely misspellings for niacin, which points to an orthography that plays by predictable English rules. No close-neighbour confusable shows up for this headword in our dataset, which usually means its spelling is distinct enough that readers don't reach for a similar-looking word instead.

Etymologically, the entry records: in 1942 derived from nicotinic + acid + vitamin, chosen to dissociate it from nicotine, to avoid the perception that vitamins or niacin-rich food contains nicotine, or that cigarettes contain vitamins. The correct English form is niacin, spelled N-I-A-C-I-N.

Definition

  1. 1
    A water-soluble vitamin, a component of vitamin B complex, found in meat, yeast, and dairy products; it is essential to metabolism.

Etymology

in 1942 derived from nicotinic + acid + vitamin, chosen to dissociate it from nicotine, to avoid the perception that vitamins or niacin-rich food contains nicotine, or that cigarettes contain vitamins.

Synonyms

E375 when used as a colour retention agentnicotinic acidvitamin B3vitamin PPvitamin P-PPP-factorpellagra-preventive factor

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "niacin"?
"niacin" is spelled N-I-A-C-I-N. The IPA pronunciation is /ˈnaɪəsɪn/.
What does "niacin" mean?
As a noun, "niacin" means: A water-soluble vitamin, a component of vitamin B complex, found in meat, yeast, and dairy products; it is essential to metabolism.
How do you pronounce "niacin"?
The IPA (International Phonetic Alphabet) transcription for "niacin" is /ˈnaɪəsɪn/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "niacin"?
in 1942 derived from nicotinic + acid + vitamin, chosen to dissociate it from nicotine, to avoid the perception that vitamins or niacin-rich food contains nicotine, or that cigarettes contain vitamins. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “niacin”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is N-I-A-C-I-N - every other letter order is a misspelling in standard orthography.
  • Say it as /ˈnaɪəsɪn/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words

Other uncommon English words near this rank

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list