methylation
/ˌmɛθɪˈleɪʃən/
"methylation" is a 11-letter English headword indexed on PlainSpell.
The verdict
“methylation” has 18 generated spelling variants in the English index at frequency #32,502. The variants make it a useful spelling check.
- #32,502
- frequency rank, English
- 36,575
- “M” headwords
- 18
- tracked misspellings
According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - The addition of a methyl group to a molecule.
Corpus desk
Index EN-methylation · methylation · English
methylation · rank #32,502 · 18 variants · 0 confusables
- FREQ-MID #32,502
- LEN-MEGA 11 letters
- VOW-5 5 vowels
- CONFUS-0 No pairs
- VAR-HIGH 18 variants
- BOOK-DENSE 36,575
- PHOTO-FINISH Micky
Nearest frequency peer: Micky (+1 rank slots)
Read with this headword: Spelling guide for this pattern
Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.
Frequency neighbourhood for “methylation”
Lower corpus rank = more everyday usage (inverted bar length for readability)
- melons
melons
67,504 corpus weight
- melton
melton
67,503 corpus weight
- mem
mem
67,502 corpus weight
- methylation
methylation
67,499 corpus weight
- Micky
Micky
67,498 corpus weight
- Milligan
Milligan
67,497 corpus weight
What this shows Bars show where “methylation” sits against the nearest ranked English headwords in the FrequencyWords band, not a reprint of letter-browse containment.
| Property | Value |
|---|---|
| Headword | methylation |
| Language | English |
| Part of speech | Noun |
| IPA | /ˌmɛθɪˈleɪʃən/ |
| Letters | 11 |
| Frequency rank | #32,502 |
| Misspellings tracked | 18 |
| Confusable pairs | 0 |
| Source | Wiktionary (kaikki.org) |
Where “methylation” sits in English frequency
A misspelling magnet
The generator records 18 spelling variants around methylation (IPA /ˌmɛθɪˈleɪʃən/), anoun. Corpus frequency is #32,502 among 36,575 “M” headwords. Wiktionary lists 2 senses, so context still picks the gloss.
Our generated misspelling index lists 18 likely wrong-spelling variants for methylation, with forms such as "emthylation", "mehtylation", and "methhylation". Each variant is a distinct typo pattern an edit-distance generator flags, typically a doubled-consonant error, a silent-letter drop, or a vowel substitution. Our dataset records no confusable match here, since nothing in our dataset looks or sounds close enough to cause mix-ups.
Etymologically, the entry records: From methyl + -ation. The correct English form is methylation, spelled M-E-T-H-Y-L-A-T-I-O-N.
Definition
- 1The addition of a methyl group to a molecule.
- 2The addition of a methyl group to cytosine and adenine residues in DNA that leads to the epigenetic modification of DNA and the reduction of gene expression and protein production.
Etymology
From methyl + -ation.
This word in other languages
Common misspellings
Also misspelled as:
- emthylation
- mehtylation
- methhylation
- methlyation
- methyaltion
- methylaiton
- methylasion
- methylatino
- methylationn
- methylatoin
- methylattion
- methyllation
- methyltaion
- methyylation
- metthylation
- metyhlation
- mmethylation
- mtehylation
Misspelling Pattern Breakdown
How far each generated variant is from the correct spelling of methylation - expressed in single-character edits (insert, delete, or swap one letter). Bigger bars stand out at a glance; a one-edit slip is the hardest to catch.
Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.
PlainSpell is rendered directly from structured Wiktionary extracts and open word-frequency lists, no number is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of May 6, 2026. Primary sources: Wiktionary (via kaikki.org) and FrequencyWords.
Frequently Asked Questions
How do you spell "methylation"?
What does "methylation" mean?
What are common misspellings of "methylation"?
How do you pronounce "methylation"?
What is the origin of the word "methylation"?
Is PlainSpell free to use?
Similar English words by spelling shape
Same letter count and similar misspelling depth for "methylation", not the corpus desk frequency band.
Same letter count
Frequency-ranked English headwords with 11 letters (nearest by frequency rank).
Similar misspelling depth
Headwords with a similar count of attested misspellings (18 here; floor ≥5).
Data Source
Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.