Skip to main content

macromolecule

ma·cro·mo·le·cule/ˈmækɹəʊˌmɒlɪkjuːl/noun

macromolecule is a noun meaning “A very large molecule, especially used in reference to large biological polymers (e.g. nucleic acids and proteins)” (English Wiktionary, September 2026). It is spelled M-A-C-R-O-M-O-L-E-C-U-L-E and has 5 syllables (ma·cro·mo·le·cule), and it appears about once in every 20 million words in written English (wordfreq, 2021 data). The plural of macromolecule is macromolecules.

What does macromolecule mean?

noun

  1. 1

    A very large molecule, especially used in reference to large biological polymers (e.g. nucleic acids and proteins).

Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).

How do you pronounce macromolecule?

  • /ˈmækɹəʊˌmɒlɪkjuːl/

Macromolecule has 5 syllables, split ma·cro·mo·le·cule in writing.

Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract). Recordings: En-us-macromolecule.ogg, Wikimedia Commons (author and licence on each file's page).

Forms of macromolecule

  • macromolecules plural

Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).

How common is macromolecule?

Macromolecule appears about once in every 20 million words in written English, the 134,976th most frequent word form in the list.

Source: written frequency: wordfreq 3.1 (a 2021 snapshot of Wikipedia, subtitles, news, books, web text and social media).

Macromolecule in Spanish, French, German and Portuguese

In the sense large molecule:

LanguageWords
GermanMakromolekül
Portuguesemacromolécula
Spanishmacromolécula

Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract). Translations are Wiktionary's, by sense; a linked word has its own PlainSpell page.

Where does macromolecule come from?

From macro- + molecule.

Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).