lysine

/ˈlaɪsin/

//ˈlaɪsin// noun

By · According to Wiktionary data (CC BY-SA) ·

"lysine" is a 6-letter English headword indexed on PlainSpell.

The verdict

“lysine” has 9 generated spelling variants in the English index at frequency #41,744. The variants make it a useful spelling check.

#41,744
frequency rank, English
2,297
“L” headwords
9
tracked misspellings
4
confusable pairs

According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - An amino acid, C₆H₁₄N₂O₂, in L- or D-forms.

Corpus desk

Index EN-lysine · lysine · English

lysine · rank #41,744 · 9 variants · 4 confusables

  • FREQ-MID #41,744
  • LEN-LONG 6 letters
  • VOW-3 3 vowels
  • CONFUS-MID 4 pairs
  • VAR-MID 9 variants
  • BOOK-MID 2,297
  • PHOTO-FINISH m9

Nearest frequency peer: m9 (+2 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Rank peers near misspelling magnet “lysine”

Same rarity band: useful when a typo lands on a peer headword

corpus weight

What this shows “lysine” sits among these FrequencyWords peers; misspelling depth is tracked separately in the edit-distance chart.

Source FrequencyWords open word-frequency list As of September 3, 2026

Visual similarity to commonly confused words

How many letter changes separate each confused pair (Levenshtein distance, normalized).

lysine vs line
67% similar
lysine vs lying
67% similar
lysine vs losing
67% similar

Source: PlainSpell confusable corpus (Wiktionary, CC BY-SA).

Key facts for lysine
PropertyValue
Headwordlysine
LanguageEnglish
Part of speechNoun
IPA/ˈlaɪsin/
Letters6
Frequency rank#41,744
Misspellings tracked9
Confusable pairs4
SourceWiktionary (kaikki.org)

Frequency seat of misspelling magnet “lysine”

Word frequency stretches from the small set of words we reach for constantly (left) out to the long tail barely used once in a while (right).lysinelands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

The axis is logarithmic, with each marked tick roughly ten times rarer than the last. Same rarity band neighbours include “m9” (#41,746), “lop” (#41,741), “Machiavelli” (#41,747). Among 2,297 “L” headwords, “lysine” is #41,744. Source: FrequencyWords open word-frequency list.

A misspelling magnet

The generator records 9 spelling variants around lysine (IPA /ˈlaɪsin/), anoun. Corpus frequency is #41,744 among 2,297 “L” headwords. Wiktionary lists 2 senses, so context still picks the gloss.

Our generated misspelling index lists 9 likely wrong-spelling variants for lysine, with forms such as "llysine", "lsyine", and "lyisne". Each of these forms differs from the correct spelling by one small edit: a doubled letter, a dropped silent letter, or a substituted vowel. It also participates in 4 confusable-pair relationships, "line", "lying", "losing", and more, since the words sound or look close enough that writers reach for the wrong one mid-sentence.

Etymologically, the entry records: From lysis + -ine, in reference to its tendency to participate in catalysis. The correct English form is lysine, spelled L-Y-S-I-N-E.

Definition

  1. 1
    An amino acid, C₆H₁₄N₂O₂, in L- or D-forms.
  2. 2
    An amino acid, C₆H₁₄N₂O₂, in L- or D-forms.

Recorded use

Wiktionary example

These source excerpts show how lysine appears in context. They illustrate usage; the definition above remains the entry’s reference meaning.

  1. Lysine is an essential amino acid required for many body functions, including growth and bone development in children; calcium absorption and maintenance of the correct nitrogen balance in the body; maintenance of lean body mass; production of antibodies, hormones, and enzymes; collagen formation and repair of tissue.

Etymology

From lysis + -ine, in reference to its tendency to participate in catalysis.

This word in other languages

lisina(Español)lysine(Français)Lysin(Deutsch)

Common misspellings

Also misspelled as:

  • llysine
  • lsyine
  • lyisne
  • lysien
  • lysinne
  • lysnie
  • lyssine
  • lyysine
  • ylsine

Misspelling Pattern Breakdown

How far each generated variant is from the correct spelling of lysine - measured in single-character edits (insert, delete, or substitute a letter). Larger bars are easier to catch; one-edit slips are the sneakiest.

llysine1lsyine2lyisne2lysien2lysinne1lysnie2lyssine1lyysine1
Edit distance from "lysine"

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "lysine"?
"lysine" is spelled L-Y-S-I-N-E. The IPA pronunciation is /ˈlaɪsin/.
What does "lysine" mean?
As a noun, "lysine" means: An amino acid, C₆H₁₄N₂O₂, in L- or D-forms.
What words are commonly confused with "lysine"?
"lysine" is commonly confused with "line", "lying", "losing". These words look or sound similar but have different meanings. PlainSpell provides detailed comparisons for each pair.
How do you pronounce "lysine"?
The IPA (International Phonetic Alphabet) transcription for "lysine" is /ˈlaɪsin/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "lysine"?
From lysis + -ine, in reference to its tendency to participate in catalysis. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "lysine", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 6 letters (nearest by frequency rank).

Malian#41,750marais#41,753leaved#41,731Lakota#41,727

Similar misspelling depth

Headwords with a similar count of attested misspellings (9 here; floor ≥5).

Kyushu9 variantsKenton9 variantsjurist9 variantsmuffler9 variants

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list