luciferase

noun

"luciferase" is a 10-letter English headword indexed on PlainSpell.

The verdict

“luciferase” is uncommon English (frequency #93,938 among 2,297 “L” headwords), classed as a noun. The kind of spelling people second-guess.

#93,938
frequency rank, English
2,297
“L” headwords

According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - Any one of a group of enzymes that produce bioluminescence by oxidizing luciferin.

Corpus desk

Index EN-luciferase · luciferase · English

luciferase · rank #93,938 · 0 variants · 0 confusables

  • FREQ-RARE #93,938
  • LEN-MEGA 10 letters
  • VOW-5 5 vowels
  • CONFUS-0 No pairs
  • VAR-0 0 variants
  • BOOK-MID 2,297
  • PHOTO-FINISH Lucey

Nearest frequency peer: Lucey (-1 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Frequency neighbourhood for “luciferase”

Lower corpus rank = more everyday usage (inverted bar length for readability)

corpus weight

What this shows Bars show where “luciferase” sits against the nearest ranked English headwords in the FrequencyWords band, not a reprint of letter-browse containment.

Source FrequencyWords open word-frequency list As of September 3, 2026
Key facts for luciferase
PropertyValue
Headwordluciferase
LanguageEnglish
Part of speechNoun
Letters10
Frequency rank#93,938
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “luciferase” sits in English frequency

Word frequency stretches from the small set of words we reach for constantly (left) out to the long tail barely used once in a while (right).luciferaselands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Ticks step logarithmically, so each one marks a roughly tenfold drop in how often the word turns up. Same rarity band neighbours include “Lucey” (#93,937), “LPT” (#93,936), “loveth” (#93,935). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

luciferase is uncommon English at frequency #93,938 among 2,297 “L” headwords, classed as anoun. Rarity is why readers land here mid-draft. Gloss: "Any one of a group of enzymes that produce bioluminescence by oxidizing luciferin.".

No generated misspelling entries exist for luciferase in our index, typically a sign the spelling maps closely to how the word sounds. Our dataset records no confusable match here, a sign it's visually distinctive enough not to be mixed up with another word.

Etymologically, the entry records: From luciferin + -ase. The correct English form is luciferase, spelled L-U-C-I-F-E-R-A-S-E.

Definition

  1. 1
    Any one of a group of enzymes that produce bioluminescence by oxidizing luciferin.

Recorded use

Wiktionary examples

These source excerpts show how luciferase appears in context. They illustrate usage; the definition above remains the entry’s reference meaning.

  1. Aptly enough, glowworms light up their underworld with a pair of chemicals that have a satanic etymology—luciferins and luciferases, after the Latin for “light bringer.”
  2. The novel coronavirus vaccine manufactured by Moderna does not contain luciferin, an organic compound involved in bioluminescence, or the enzyme luciferase, contrary to claims on social media.

Etymology

From luciferin + -ase.

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "luciferase"?
"luciferase" is spelled L-U-C-I-F-E-R-A-S-E.
What does "luciferase" mean?
As a noun, "luciferase" means: Any one of a group of enzymes that produce bioluminescence by oxidizing luciferin.
What is the origin of the word "luciferase"?
From luciferin + -ase. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "luciferase", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 10 letters (nearest by frequency rank).

What to do next

You've looked up "luciferase". Here's where to go from here.

  • Usage frequency rank #93,938 among English headwords in this corpus. Corpus statistics
  • Browse more English words in the "L" letter cohort. L–Z browse
  • PlainSpell rotates a curated Word of the Day from the English corpus, a passive way to discover vocabulary. Word of the Day

PlainSpell is a reference corpus, not spelling advice. Verify unusual forms in context.

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list