lissencephaly
/ˌlɪs.ɛnˈsɛf.əl.i/noun
lissencephaly is spelled L-I-S-S-E-N-C-E-P-H-A-L-Y: 13 letters. It appears about once in every 44 million words in written English, the 204,233rd most frequent word form (wordfreq, 2021 data). As a noun, lissencephaly means “The condition of having a smooth appearance on the surface of the brain” (English Wiktionary, September 2026).
How many letters and syllables are in lissencephaly?
| Letters | 13: L-I-S-S-E-N-C-E-P-H-A-L-Y |
|---|---|
| In writing | about once in every 44 million words; the 204,233rd most frequent word form |
| Wrong spellings searched | none measured in search |
Sources: letters and syllables from the English Wiktionary's hyphenation or pronunciation; written frequency: wordfreq 3.1 (a 2021 snapshot of Wikipedia, subtitles, news, books, web text and social media).
How common is lissencephaly?
Lissencephaly appears about once in every 44 million words in written English, the 204,233rd most frequent word form in the list.
Source: written frequency: wordfreq 3.1 (a 2021 snapshot of Wikipedia, subtitles, news, books, web text and social media).
How do you pronounce lissencephaly?
- /ˌlɪs.ɛnˈsɛf.əl.i/
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).
What does lissencephaly mean?
The meanings the English Wiktionary records, quoted as written there (source below).
noun
- 1
The condition of having a smooth appearance on the surface of the brain.
- 2
An abnormality of brain development marked by the presence of a smooth cerebral cortex with few or no convolutions; frequently associated with severe developmental disability.
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).
Lissencephaly in Spanish, French, German and Portuguese
In the sense disorder characterized by the lack of folds and grooves of the brain:
| Language | Words |
|---|---|
| French | lissencéphalie |
| German | Lissenzephalie |
| Portuguese | lisencefalia |
| Spanish | lisencefalia |
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract). Translations are Wiktionary's, by sense; a linked word has its own PlainSpell page.
Where does lissencephaly come from?
From Ancient Greek λισσός (lissós, “smooth”) + encephal- (“brain”) + -y, from Ancient Greek ἐν (en, “in”) + κεφαλή (kephalḗ, “head”).
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).