hydrolase
/ˈhaɪdɹəleɪz/
"hydrolase" is a 9-letter English headword indexed on PlainSpell.
The verdict
“hydrolase” is uncommon English (frequency #97,127 among 2,646 “H” headwords), classed as a noun. The kind of spelling people second-guess.
- #97,127
- frequency rank, English
- 2,646
- “H” headwords
According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - An enzyme that catalyzes the hydrolysis of a substrate.
Corpus desk
Index EN-hydrolase · hydrolase · English
hydrolase · rank #97,127 · 0 variants · 0 confusables
- FREQ-RARE #97,127
- LEN-LONG 9 letters
- VOW-4 4 vowels
- CONFUS-0 No pairs
- VAR-0 0 variants
- BOOK-MID 2,646
- PHOTO-FINISH hydrogeology
Nearest frequency peer: hydrogeology (-1 rank slots)
Read with this headword: Spelling guide for this pattern
Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.
Long-tail ranks near “hydrolase”
Sparse band: bars invert rank so rarer forms read shorter
- Hurstville
Hurstville
2,877 corpus weight
- hydrogeology
hydrogeology
2,875 corpus weight
- hydrolase
hydrolase
2,874 corpus weight
- hydromorpho…
hydromorphone
2,873 corpus weight
- hyp
hyp
2,872 corpus weight
- hyperspectr…
hyperspectral
2,871 corpus weight
What this shows Long-tail view: where “hydrolase” sits against similarly uncommon English ranks.
| Property | Value |
|---|---|
| Headword | hydrolase |
| Language | English |
| Part of speech | Noun |
| IPA | /ˈhaɪdɹəleɪz/ |
| Letters | 9 |
| Frequency rank | #97,127 |
| Misspellings tracked | 0 |
| Confusable pairs | 0 |
| Source | Wiktionary (kaikki.org) |
Long-tail rank of “hydrolase” in English
Rare enough to double-check
hydrolase is uncommon English at frequency #97,127 among 2,646 “H” headwords, classed as anoun, transcribed /ˈhaɪdɹəleɪz/. Rarity is why readers land here mid-draft. Gloss: "An enzyme that catalyzes the hydrolysis of a substrate.".
We couldn't generate a plausible misspelling set for hydrolase, since its letter pattern doesn't lend itself to common typo substitutions. This entry stands alone in our confusable dataset, a sign it's visually distinctive enough not to be mixed up with another word.
Etymologically, the entry records: From hydrolysis + -ase. The correct English form is hydrolase, spelled H-Y-D-R-O-L-A-S-E.
Definition
- 1An enzyme that catalyzes the hydrolysis of a substrate.
Etymology
From hydrolysis + -ase.
Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.
Frequently Asked Questions
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Similar English words by spelling shape
Same letter count and similar misspelling depth for "hydrolase", not the corpus desk frequency band.
Same letter count
Frequency-ranked English headwords with 9 letters (nearest by frequency rank).