holoprosencephaly
noun
holoprosencephaly is spelled H-O-L-O-P-R-O-S-E-N-C-E-P-H-A-L-Y: 17 letters. It appears about once in every 72 million words in written English, the 269,040th most frequent word form (wordfreq, 2021 data). As a noun, holoprosencephaly means “A congenital disorder involving insufficient division of the lobes of the brain during fetal development, resulting in skull and facial deformities…” (English Wiktionary, September 2026). The plural of holoprosencephaly is holoprosencephalies.
How many letters and syllables are in holoprosencephaly?
| Letters | 17: H-O-L-O-P-R-O-S-E-N-C-E-P-H-A-L-Y |
|---|---|
| In writing | about once in every 72 million words; the 269,040th most frequent word form |
| Wrong spellings searched | none measured in search |
Sources: letters and syllables from the English Wiktionary's hyphenation or pronunciation; written frequency: wordfreq 3.1 (a 2021 snapshot of Wikipedia, subtitles, news, books, web text and social media).
How common is holoprosencephaly?
Holoprosencephaly appears about once in every 72 million words in written English, the 269,040th most frequent word form in the list.
Source: written frequency: wordfreq 3.1 (a 2021 snapshot of Wikipedia, subtitles, news, books, web text and social media).
Forms of holoprosencephaly
- holoprosencephalies plural
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).
What does holoprosencephaly mean?
The meanings the English Wiktionary records, quoted as written there (source below).
noun
- 1
A congenital disorder involving insufficient division of the lobes of the brain during fetal development, resulting in skull and facial deformities ranging from minor cleft lip problems to cyclopia, in which a single eye develops where the nose would normally be.
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).
How do you abbreviate holoprosencephaly?
Wiktionary records one abbreviation of holoprosencephaly: HPE.
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).
Holoprosencephaly in Spanish, French, German and Portuguese
In the sense a congenital disorder involving insufficient division of the lobes of the brain:
| Language | Words |
|---|---|
| Portuguese | holoprosencefalia, arrinencefalia |
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract). Translations are Wiktionary's, by sense; a linked word has its own PlainSpell page.
Where does holoprosencephaly come from?
From Ancient Greek ὅλος (hólos, “whole”) + πρόσω (prósō, “forwards, onwards”) (referring to the prosencephalon (“forebrain”)) + ἐγκέφαλος (enképhalos, “brain”) + English -y (suffix denoting a condition), i.e. “condition of a whole (inappropriately divided) forebrain”. By surface analysis, holo- + pros- + encephal- + -y.
Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).