heterozygous

adj

"heterozygous" is a 12-letter English headword indexed on PlainSpell.

The verdict

“heterozygous” is uncommon English (frequency #62,198 among 2,646 “H” headwords), classed as an adjective. The kind of spelling people second-guess.

#62,198
frequency rank, English
2,646
“H” headwords

According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - Of an organism: having two different alleles in a given gene.

Corpus desk

Index EN-heterozygous · heterozygous · English

heterozygous · rank #62,198 · 0 variants · 0 confusables

  • FREQ-RARE #62,198
  • LEN-MEGA 12 letters
  • VOW-6 6 vowels
  • CONFUS-0 No pairs
  • VAR-0 0 variants
  • BOOK-MID 2,646
  • PHOTO-FINISH hermetically

Nearest frequency peer: hermetically (-1 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Long-tail ranks near “heterozygous”

Sparse band: bars invert rank so rarer forms read shorter

corpus weight

What this shows Long-tail view: where “heterozygous” sits against similarly uncommon English ranks.

Source FrequencyWords open word-frequency list As of September 3, 2026
Key facts for heterozygous
PropertyValue
Headwordheterozygous
LanguageEnglish
Part of speechAdjective
Letters12
Frequency rank#62,198
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Long-tail rank of “heterozygous” in English

Word frequency stretches from the small set of words we reach for constantly (left) out to the long tail barely used once in a while (right).heterozygousfalls in this rarity band:

#1#100#1K#10K#100K
← used constantlyrarely used →

The axis is logarithmic, with each marked tick roughly ten times rarer than the last. Rare peers in the same band: “hermetically” (#62,197), “Higginbotham” (#62,199), “Heo” (#62,196). Among 2,646 “H” headwords, “heterozygous” is #62,198. Source: FrequencyWords open word-frequency list.

Rare enough to double-check

heterozygous is uncommon English at frequency #62,198 among 2,646 “H” headwords, classed as anadjective. Rarity is why readers land here mid-draft. Gloss: "Of an organism: having two different alleles in a given gene.".

Zero misspellings are on record for heterozygous in our index, since its letter sequence doesn't invite the usual edit-distance slips. Our confusable-pair dataset has no match for it, which typically means the spelling is too distinctive to be mistaken for another word.

Etymologically, the entry records: From hetero- + -zygous. The correct English form is heterozygous, spelled H-E-T-E-R-O-Z-Y-G-O-U-S.

Definition

  1. 1
    Of an organism: having two different alleles in a given gene.

Recorded use

Wiktionary example

These source excerpts show how heterozygous appears in context. They illustrate usage; the definition above remains the entry’s reference meaning.

  1. Plant breeding is always a numbers game.[…]The wild species we use are rich in genetic variation, and individual plants are highly heterozygous and do not breed true. In addition, we are looking for rare alleles, so the more plants we try, the better.

Etymology

From hetero- + -zygous.

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "heterozygous"?
"heterozygous" is spelled H-E-T-E-R-O-Z-Y-G-O-U-S.
What does "heterozygous" mean?
As an adjective, "heterozygous" means: Of an organism: having two different alleles in a given gene.
What is the origin of the word "heterozygous"?
From hetero- + -zygous. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "heterozygous", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 12 letters (nearest by frequency rank).

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list