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frameshift

noun, verb

frameshift is a noun meaning “A frameshift mutation” (English Wiktionary, September 2026). It is spelled F-R-A-M-E-S-H-I-F-T, and it appears about once in every 21 million words in written English (wordfreq, 2021 data). The plural of frameshift is frameshifts.

What does frameshift mean?

noun

  1. 1

    A frameshift mutation.

verb

  1. 1

    To use a starting point for translating a series of nucleotides that is off by an amount not divisible by three, resulting in an entirely distinct set of codons.

Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).

Forms of frameshift

  • frameshifts plural, present, singular, he/she/it
  • frameshifting participle, present
  • frameshifted participle, past

Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).

How common is frameshift?

Frameshift appears about once in every 21 million words in written English, the 139,999th most frequent word form in the list.

Source: written frequency: wordfreq 3.1 (a 2021 snapshot of Wikipedia, subtitles, news, books, web text and social media).

Where does frameshift come from?

From frame + shift.

Source: English Wiktionary, dump of September 2, 2026 (CC BY-SA 4.0), through kaikki.org (Wiktextract).