epigenetics

/ˌɛpɪd͡ʒəˈnɛtɪks/

//ˌɛpɪd͡ʒəˈnɛtɪks// noun

"epigenetics" is a 11-letter English headword indexed on PlainSpell.

The verdict

“epigenetics” is uncommon English (frequency #59,371 among 18,836 “E” headwords), classed as a noun. The kind of spelling people second-guess.

#59,371
frequency rank, English
18,836
“E” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - The study of the processes involved in the genetic development of an organism, especially the activation and deactivation of genes.

Key facts for epigenetics
PropertyValue
Headwordepigenetics
LanguageEnglish
Part of speechNoun
IPA/ˌɛpɪd͡ʒəˈnɛtɪks/
Letters11
Frequency rank#59,371
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “epigenetics” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). epigenetics lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

epigenetics is uncommon English at frequency #59,371 among 18,836 “E” headwords, classed as anoun, transcribed /ˌɛpɪd͡ʒəˈnɛtɪks/. Rarity is why readers land here mid-draft. 2 senses are on record.

No generated misspelling entries exist for epigenetics in our index, a straightforward case of a spelling with little room for common typos. It is not paired with a close-neighbour confusable in our dataset, which tends to mean the word is visually distinctive enough to stand on its own.

Etymologically, the entry records: Blend of epigenesis + genetics; coined by C. H. Waddington in 1942. The correct English form is epigenetics, spelled E-P-I-G-E-N-E-T-I-C-S.

Definition

  1. 1
    The study of the processes involved in the genetic development of an organism, especially the activation and deactivation of genes.
  2. 2
    The study of heritable changes caused by the activation and deactivation of genes without any change in DNA sequence.

Etymology

Blend of epigenesis + genetics; coined by C. H. Waddington in 1942.

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "epigenetics"?
"epigenetics" is spelled E-P-I-G-E-N-E-T-I-C-S. The IPA pronunciation is /ˌɛpɪd͡ʒəˈnɛtɪks/.
What does "epigenetics" mean?
As a noun, "epigenetics" means: The study of the processes involved in the genetic development of an organism, especially the activation and deactivation of genes.
How do you pronounce "epigenetics"?
The IPA (International Phonetic Alphabet) transcription for "epigenetics" is /ˌɛpɪd͡ʒəˈnɛtɪks/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "epigenetics"?
Blend of epigenesis + genetics; coined by C. H. Waddington in 1942. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “epigenetics”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is E-P-I-G-E-N-E-T-I-C-S - every other letter order is a misspelling in standard orthography.
  • Say it as /ˌɛpɪd͡ʒəˈnɛtɪks/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words

Other uncommon English words near this rank

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list