endorphin

/ɛnˈdɔːfɪn/

//ɛnˈdɔːfɪn// noun

"endorphin" is a 9-letter English headword indexed on PlainSpell.

The verdict

“endorphin” is uncommon English (frequency #70,637 among 18,836 “E” headwords), classed as a noun. The kind of spelling people second-guess.

#70,637
frequency rank, English
18,836
“E” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - Any of a group of peptide hormones found in the mammalian brain that act as neurotransmitters and have properties similar to morphine.

Key facts for endorphin
PropertyValue
Headwordendorphin
LanguageEnglish
Part of speechNoun
IPA/ɛnˈdɔːfɪn/
Letters9
Frequency rank#70,637
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “endorphin” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). endorphin lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

endorphin is uncommon English at frequency #70,637 among 18,836 “E” headwords, classed as anoun, transcribed /ɛnˈdɔːfɪn/. Rarity is why readers land here mid-draft. Gloss: "Any of a group of peptide hormones found in the mammalian brain that act as neurotransmitters and have properties similar to morphine.".

endorphin doesn't appear in our generated misspelling index, a sign its spelling follows regular English conventions. No close-neighbour confusable shows up for this headword in our dataset, a sign it's visually distinctive enough not to be mixed up with another word.

Etymologically, the entry records: Borrowed from French endorphine, from endo(gène) (“endogenous, produced within”) and morphine. The correct English form is endorphin, spelled E-N-D-O-R-P-H-I-N.

Definition

  1. 1
    Any of a group of peptide hormones found in the mammalian brain that act as neurotransmitters and have properties similar to morphine.

Etymology

Borrowed from French endorphine, from endo(gène) (“endogenous, produced within”) and morphine.

This word in other languages

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "endorphin"?
"endorphin" is spelled E-N-D-O-R-P-H-I-N. The IPA pronunciation is /ɛnˈdɔːfɪn/.
What does "endorphin" mean?
As a noun, "endorphin" means: Any of a group of peptide hormones found in the mammalian brain that act as neurotransmitters and have properties similar to morphine.
How do you pronounce "endorphin"?
The IPA (International Phonetic Alphabet) transcription for "endorphin" is /ɛnˈdɔːfɪn/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "endorphin"?
Borrowed from French endorphine, from endo(gène) (“endogenous, produced within”) and morphine. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “endorphin”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is E-N-D-O-R-P-H-I-N - every other letter order is a misspelling in standard orthography.
  • Say it as /ɛnˈdɔːfɪn/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words

Other uncommon English words near this rank

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list