disulfide

/daɪˈsʌlfaɪd/

//daɪˈsʌlfaɪd// noun

"disulfide" is a 9-letter English headword indexed on PlainSpell.

The verdict

“disulfide” is a moderately-common English word, ranked #48,705 in English word frequency and used as a noun.

#48,705
frequency rank, English
9
letters
13
tracked misspellings

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - A functional group with two sulfur atoms bonded to one another, described by the following formula: R–S–S–R'.

Key facts for disulfide
PropertyValue
Headworddisulfide
LanguageEnglish
Part of speechNoun
IPA/daɪˈsʌlfaɪd/
Letters9
Frequency rank#48,705
Misspellings tracked13
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “disulfide” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). disulfide lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Spelling & Dictionary Insight

The English entry for disulfide is 9 letters long, classified as a noun, and transcribed in the International Phonetic Alphabet as /daɪˈsʌlfaɪd/. Corpus data places it at rank #48,705 in overall English word frequency, marking it as uncommon enough that many writers pause before typing it. Wiktionary records 3 distinct senses for this headword, so context determines which meaning a reader should apply.

Our generated misspelling index lists 13 likely wrong-spelling variants for disulfide, with forms such as "ddisulfide", "dislufide", and "dissulfide". Each of these forms differs from the correct spelling by one small edit: a doubled letter, a dropped silent letter, or a substituted vowel. No close-neighbour confusable shows up for this headword in our dataset, a sign it's visually distinctive enough not to be mixed up with another word.

Etymologically, the entry records: From di- + sulfide. The correct English form is disulfide, spelled D-I-S-U-L-F-I-D-E.

Definition

  1. 1
    A functional group with two sulfur atoms bonded to one another, described by the following formula: R–S–S–R'.
  2. 2
    The anion ⁻S–S⁻.
  3. 3
    A binary compound of sulfur and another element in the ratio 2:1 (formula XS₂).

Etymology

From di- + sulfide.

Synonyms

anion −S–S−

Common misspellings

Also misspelled as: ddisulfide,dislufide,dissulfide,disuflide,disulfdie,disulffide,disulfidde,disulfied,disulifde,disullfide,diuslfide,dsiulfide,idsulfide

Misspelling Pattern Breakdown

How far each generated variant is from the correct spelling of disulfide - counted as single-character edits (an insertion, a deletion, or a substituted letter). The larger the bar, the easier the typo is to spot; one-edit slips are the ones that sneak past readers.

ddisulfide1dislufide2dissulfide1disuflide2disulfdie2disulffide1disulfidde1disulfied2
Edit distance from "disulfide"

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "disulfide"?
"disulfide" is spelled D-I-S-U-L-F-I-D-E. The IPA pronunciation is /daɪˈsʌlfaɪd/.
What does "disulfide" mean?
As a noun, "disulfide" means: A functional group with two sulfur atoms bonded to one another, described by the following formula: R–S–S–R'.
What are common misspellings of "disulfide"?
Common misspellings include "ddisulfide", "dislufide", "dissulfide", "disuflide", "disulfdie". The correct spelling is "disulfide".
How do you pronounce "disulfide"?
The IPA (International Phonetic Alphabet) transcription for "disulfide" is /daɪˈsʌlfaɪd/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "disulfide"?
From di- + sulfide. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “disulfide”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is D-I-S-U-L-F-I-D-E - every other letter order is a misspelling in standard orthography.
  • Say it as /daɪˈsʌlfaɪd/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words
Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list FrequencyWords open word-frequency list