demethylation
"demethylation" is a 13-letter English headword indexed on PlainSpell.
The verdict
“demethylation” is uncommon English (outside the top frequency list), classed as a noun. The kind of spelling people second-guess.
- Unranked
- below top-frequency English
- 13
- letters
According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - The removal of one or more methyl groups from a molecule.
Corpus desk
Index EN-demethylation · demethylation · English
demethylation · unranked · 0 variants · 0 confusables
- FREQ-UNRANKED Unranked
- LEN-MEGA 13 letters
- VOW-6 6 vowels
- CONFUS-0 No pairs
- VAR-0 0 variants
- BOOK-THIN "D" thin
- PHOTO-UNK Peer pending
Read with this headword: Spelling guide for this pattern
Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.
| Property | Value |
|---|---|
| Headword | demethylation |
| Language | English |
| Part of speech | Noun |
| Letters | 13 |
| Misspellings tracked | 0 |
| Confusable pairs | 0 |
| Source | Wiktionary (kaikki.org) |
Where “demethylation” sits in English frequency
Rare enough to double-check
demethylation is uncommon English outside the top frequency list, classed as anoun. Rarity is why readers land here mid-draft. Gloss: "The removal of one or more methyl groups from a molecule.".
Our edit-distance generator produced no likely misspellings for demethylation, which points to an orthography that plays by predictable English rules. It is not paired with a close-neighbour confusable in our dataset, since its spelling is unusual enough that it doesn't cluster with a lookalike.
Etymologically, the entry records: From de- + methylation. The correct English form is demethylation, spelled D-E-M-E-T-H-Y-L-A-T-I-O-N.
Definition
- 1The removal of one or more methyl groups from a molecule.
Recorded use
Wiktionary exampleThese source excerpts show how demethylation appears in context. They illustrate usage; the definition above remains the entry’s reference meaning.
That imprinted genes escape demethylation is, we now know, all that stood between science and the cloning of mammals for many years.
Etymology
From de- + methylation.
Antonyms
Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA). See the methodology for how each field is sourced and updated.
Frequently Asked Questions
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Data Source
Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.