anaphylaxis

/ˌænəfɪˈlæksɪs/

//ˌænəfɪˈlæksɪs// noun

"anaphylaxis" is a 11-letter English headword indexed on PlainSpell.

The verdict

“anaphylaxis” is a moderately-common English word, ranked #47,462 in English word frequency and used as a noun.

#47,462
frequency rank, English
11
letters
17
tracked misspellings

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - Extreme sensitivity to a substance such as a foreign protein or drug.

Key facts for anaphylaxis
PropertyValue
Headwordanaphylaxis
LanguageEnglish
Part of speechNoun
IPA/ˌænəfɪˈlæksɪs/
Letters11
Frequency rank#47,462
Misspellings tracked17
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “anaphylaxis” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). anaphylaxis lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Spelling & Dictionary Insight

The English entry for anaphylaxis is 11 letters long, classified as a noun, and transcribed in the International Phonetic Alphabet as /ˌænəfɪˈlæksɪs/. Corpus data places it at rank #47,462 in overall English word frequency, marking it as uncommon enough that many writers pause before typing it. Wiktionary records 2 distinct senses for this headword, so context determines which meaning a reader should apply.

Our generated misspelling index lists 17 likely wrong-spelling variants for anaphylaxis, with forms such as "aanphylaxis", "anahpylaxis", and "anaphhylaxis". Each variant is a distinct typo pattern an edit-distance generator flags, typically a doubled-consonant error, a silent-letter drop, or a vowel substitution. Our dataset records no confusable match here, a sign it's visually distinctive enough not to be mixed up with another word.

Etymologically, the entry records: Borrowed from French anaphylaxie, coined by French physiologist and parapsychologist Charles Richet and French zoologist Paul Portier from the Ancient Greek ᾰ̓νᾰ- (ănă-, “(intensifier) thoroughly”) from ᾰ̓νᾰ́ (ănắ, “to, again, upon”) and φύλαξις (phúlaxis, … The correct English form is anaphylaxis, spelled A-N-A-P-H-Y-L-A-X-I-S.

Definition

  1. 1
    Extreme sensitivity to a substance such as a foreign protein or drug.
  2. 2
    A severe and rapid systemic allergic reaction to an allergen, causing a constriction of the trachea, preventing breathing; anaphylactic shock.

Etymology

Borrowed from French anaphylaxie, coined by French physiologist and parapsychologist Charles Richet and French zoologist Paul Portier from the Ancient Greek ᾰ̓νᾰ- (ănă-, “(intensifier) thoroughly”) from ᾰ̓νᾰ́ (ănắ, “to, again, upon”) and φύλαξις (phúlaxis, “protection, watching, guarding”).

This word in other languages

Common misspellings

Also misspelled as: aanphylaxis,anahpylaxis,anaphhylaxis,anaphlyaxis,anaphyalxis,anaphylaixs,anaphylaxiss,anaphylaxsi,anaphylaxxis,anaphyllaxis,anaphylxais,anaphyylaxis,anapphylaxis,anapyhlaxis,annaphylaxis,anpahylaxis,naaphylaxis

Misspelling Pattern Breakdown

How far each generated variant is from the correct spelling of anaphylaxis - measured in single-character edits (insert, delete, or substitute a letter). Larger bars are easier to catch; one-edit slips are the sneakiest.

aanphylaxis2anahpylaxis2anaphhylaxis1anaphlyaxis2anaphyalxis2anaphylaixs2anaphylaxiss1anaphylaxsi2
Edit distance from "anaphylaxis"

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "anaphylaxis"?
"anaphylaxis" is spelled A-N-A-P-H-Y-L-A-X-I-S. The IPA pronunciation is /ˌænəfɪˈlæksɪs/.
What does "anaphylaxis" mean?
As a noun, "anaphylaxis" means: Extreme sensitivity to a substance such as a foreign protein or drug.
What are common misspellings of "anaphylaxis"?
Common misspellings include "aanphylaxis", "anahpylaxis", "anaphhylaxis", "anaphlyaxis", "anaphyalxis". The correct spelling is "anaphylaxis".
How do you pronounce "anaphylaxis"?
The IPA (International Phonetic Alphabet) transcription for "anaphylaxis" is /ˌænəfɪˈlæksɪs/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "anaphylaxis"?
Borrowed from French anaphylaxie, coined by French physiologist and parapsychologist Charles Richet and French zoologist Paul Portier from the Ancient Greek ᾰ̓νᾰ- (ănă-, “(intensifier) thoroughly”) from ᾰ̓νᾰ́ (ănắ, “to, again, upon”) and φύλαξις (... See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “anaphylaxis”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is A-N-A-P-H-Y-L-A-X-I-S - every other letter order is a misspelling in standard orthography.
  • Say it as /ˌænəfɪˈlæksɪs/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words
Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list FrequencyWords open word-frequency list