bupropion

/bjuːˈpɹəʊ.pi.ən/

//bjuːˈpɹəʊ.pi.ən// noun

By · According to Wiktionary data (CC BY-SA) ·

"bupropion" is a 9-letter English headword indexed on PlainSpell.

The verdict

“bupropion” is uncommon English (frequency #90,236 among 31,241 “B” headwords), classed as a noun. The kind of spelling people second-guess.

#90,236
frequency rank, English
31,241
“B” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - An antidepressant drug which is also given to relieve the symptoms of nicotine withdrawal.

Key facts for bupropion
PropertyValue
Headwordbupropion
LanguageEnglish
Part of speechNoun
IPA/bjuːˈpɹəʊ.pi.ən/
Letters9
Frequency rank#90,236
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “bupropion” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). bupropion lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

bupropion is uncommon English at frequency #90,236 among 31,241 “B” headwords, classed as anoun, transcribed /bjuːˈpɹəʊ.pi.ən/. Rarity is why readers land here mid-draft. Gloss: "An antidepressant drug which is also given to relieve the symptoms of nicotine withdrawal.".

Zero misspellings are on record for bupropion in our index, a straightforward case of a spelling with little room for common typos. We don't track a confusable pairing for this entry, which usually means its spelling is distinct enough that readers don't reach for a similar-looking word instead.

Etymologically, the entry records: Blend of bu(tyl) + propion(yl). The correct English form is bupropion, spelled B-U-P-R-O-P-I-O-N.

Definition

  1. 1
    An antidepressant drug which is also given to relieve the symptoms of nicotine withdrawal.

Etymology

Blend of bu(tyl) + propion(yl).

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "bupropion"?
"bupropion" is spelled B-U-P-R-O-P-I-O-N. The IPA pronunciation is /bjuːˈpɹəʊ.pi.ən/.
What does "bupropion" mean?
As a noun, "bupropion" means: An antidepressant drug which is also given to relieve the symptoms of nicotine withdrawal.
How do you pronounce "bupropion"?
The IPA (International Phonetic Alphabet) transcription for "bupropion" is /bjuːˈpɹəʊ.pi.ən/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "bupropion"?
Blend of bu(tyl) + propion(yl). See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “bupropion”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is B-U-P-R-O-P-I-O-N - every other letter order is a misspelling in standard orthography.
  • Say it as /bjuːˈpɹəʊ.pi.ən/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words

Other uncommon English words near this rank

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list