syndrome

/ˈsɪndɹəʊm/

//ˈsɪndɹəʊm// noun

"syndrome" is a 8-letter English headword indexed on PlainSpell.

The verdict

“syndrome” has 13 generated spelling variants in the English index at frequency #4,903. The variants make it a useful spelling check.

#4,903
frequency rank, English
54,294
“S” headwords
13
tracked misspellings

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - A recognizable pattern of signs, symptoms and/or behaviours, especially of a disease or medical or psychological condition.

Key facts for syndrome
PropertyValue
Headwordsyndrome
LanguageEnglish
Part of speechNoun
IPA/ˈsɪndɹəʊm/
Letters8
Frequency rank#4,903
Misspellings tracked13
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “syndrome” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). syndrome lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

A misspelling magnet

The generator records 13 spelling variants around syndrome (IPA /ˈsɪndɹəʊm/), anoun. Corpus frequency is #4,903 among 54,294 “S” headwords. Wiktionary lists 2 senses, so context still picks the gloss.

Our generated misspelling index lists 13 likely wrong-spelling variants for syndrome, with forms such as "snydrome", "ssyndrome", and "sydnrome". Each of these forms differs from the correct spelling by one small edit: a doubled letter, a dropped silent letter, or a substituted vowel. This entry stands alone in our confusable dataset, suggesting its spelling stands apart enough that readers rarely confuse it with something else.

Etymologically, the entry records: Learned borrowing from New Latin syndrome, from Ancient Greek συνδρομή (sundromḗ, “concurrence of symptoms, concourse”), from σύνδρομος (súndromos, “running together”), from συν- (sun-, “with”) + δρόμος (drómos, “running, course”). The correct English form is syndrome, spelled S-Y-N-D-R-O-M-E.

Definition

  1. 1
    A recognizable pattern of signs, symptoms and/or behaviours, especially of a disease or medical or psychological condition.
  2. 2
    Any set of characteristics regarded as identifying a certain type, condition, etc., usually adverse.

Etymology

Learned borrowing from New Latin syndrome, from Ancient Greek συνδρομή (sundromḗ, “concurrence of symptoms, concourse”), from σύνδρομος (súndromos, “running together”), from συν- (sun-, “with”) + δρόμος (drómos, “running, course”).

Synonyms

This word in other languages

Common misspellings

Also misspelled as:

  • snydrome
  • ssyndrome
  • sydnrome
  • synddrome
  • syndorme
  • syndrmoe
  • syndroem
  • syndromme
  • syndrrome
  • synndrome
  • synrdome
  • syyndrome
  • ysndrome

Misspelling Pattern Breakdown

How far each generated variant is from the correct spelling of syndrome - expressed in single-character edits (insert, delete, or swap one letter). Bigger bars stand out at a glance; a one-edit slip is the hardest to catch.

snydrome2ssyndrome1sydnrome2synddrome1syndorme2syndrmoe2syndroem2syndromme1
Edit distance from "syndrome"

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "syndrome"?
"syndrome" is spelled S-Y-N-D-R-O-M-E. The IPA pronunciation is /ˈsɪndɹəʊm/.
What does "syndrome" mean?
As a noun, "syndrome" means: A recognizable pattern of signs, symptoms and/or behaviours, especially of a disease or medical or psychological condition.
What are common misspellings of "syndrome"?
Common misspellings include "snydrome", "ssyndrome", "sydnrome", "synddrome", "syndorme". The correct spelling is "syndrome".
How do you pronounce "syndrome"?
The IPA (International Phonetic Alphabet) transcription for "syndrome" is /ˈsɪndɹəʊm/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "syndrome"?
Learned borrowing from New Latin syndrome, from Ancient Greek συνδρομή (sundromḗ, “concurrence of symptoms, concourse”), from σύνδρομος (súndromos, “running together”), from συν- (sun-, “with”) + δρόμος (drómos, “running, course”). See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Using “syndrome”

The practical upshot for anyone who landed here from a spell-check.

  • The one correct English spelling is S-Y-N-D-R-O-M-E - every other letter order is a misspelling in standard orthography.
  • Say it as /ˈsɪndɹəʊm/ (IPA); tap the speaker on the pronunciation badge to hear it where audio exists.
  • Browse more English words and confusable pairs in the same reference. English words

Same frequency band

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list FrequencyWords open word-frequency list