syndrome

/ˈsɪndɹəʊm/

//ˈsɪndɹəʊm// noun

By · According to Wiktionary data (CC BY-SA) ·

"syndrome" is a 8-letter English headword indexed on PlainSpell.

The verdict

“syndrome” has 13 generated spelling variants in the English index at frequency #4,903. The variants make it a useful spelling check.

#4,903
frequency rank, English
6,566
“S” headwords
13
tracked misspellings

According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - A recognizable pattern of signs, symptoms and/or behaviours, especially of a disease or medical or psychological condition.

Corpus desk

Index EN-syndrome · syndrome · English

syndrome · rank #4,903 · 13 variants · 0 confusables

  • FREQ-COMMON #4,903
  • LEN-LONG 8 letters
  • VOW-3 3 vowels
  • CONFUS-0 No pairs
  • VAR-HIGH 13 variants
  • BOOK-DENSE 6,566
  • PHOTO-FINISH Switzerland

Nearest frequency peer: Switzerland (-1 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Rank peers near misspelling magnet “syndrome”

Same rarity band: useful when a typo lands on a peer headword

corpus weight

What this shows “syndrome” sits among these FrequencyWords peers; misspelling depth is tracked separately in the edit-distance chart.

Source FrequencyWords open word-frequency list As of September 3, 2026
Key facts for syndrome
PropertyValue
Headwordsyndrome
LanguageEnglish
Part of speechNoun
IPA/ˈsɪndɹəʊm/
Letters8
Frequency rank#4,903
Misspellings tracked13
Confusable pairs0
SourceWiktionary (kaikki.org)

Frequency seat of misspelling magnet “syndrome”

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right).syndromelands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Same rarity band neighbours include “Switzerland” (#4,902), “tasks” (#4,904), “suggestion” (#4,901). Among 6,566 “S” headwords, “syndrome” is #4,903. Source: FrequencyWords open word-frequency list.

A misspelling magnet

The generator records 13 spelling variants around syndrome (IPA /ˈsɪndɹəʊm/), anoun. Corpus frequency is #4,903 among 6,566 “S” headwords. Wiktionary lists 2 senses, so context still picks the gloss.

Our generated misspelling index lists 13 likely wrong-spelling variants for syndrome, with forms such as "snydrome", "ssyndrome", and "sydnrome". Each of these forms differs from the correct spelling by one small edit: a doubled letter, a dropped silent letter, or a substituted vowel. This entry stands alone in our confusable dataset, suggesting its spelling stands apart enough that readers rarely confuse it with something else.

Etymologically, the entry records: Learned borrowing from New Latin syndrome, from Ancient Greek συνδρομή (sundromḗ, “concurrence of symptoms, concourse”), from σύνδρομος (súndromos, “running together”), from συν- (sun-, “with”) + δρόμος (drómos, “running, course”). The correct English form is syndrome, spelled S-Y-N-D-R-O-M-E.

Definition

  1. 1
    A recognizable pattern of signs, symptoms and/or behaviours, especially of a disease or medical or psychological condition.
  2. 2
    Any set of characteristics regarded as identifying a certain type, condition, etc., usually adverse.

Recorded use

Wiktionary examples

These source excerpts show how syndrome appears in context. They illustrate usage; the definition above remains the entry’s reference meaning.

  1. Down syndrome; acquired immune deficiency syndrome; restless-leg syndrome; battered-wife syndrome
  2. A “zone of rarity” emerges when symptoms cluster neatly into syndromes and interforms are uncommon, although not altogether absent. Fuzzy boundaries and interforms are a special problem for PTSD […]

Etymology

Learned borrowing from New Latin syndrome, from Ancient Greek συνδρομή (sundromḗ, “concurrence of symptoms, concourse”), from σύνδρομος (súndromos, “running together”), from συν- (sun-, “with”) + δρόμος (drómos, “running, course”).

Synonyms

syndrome

This word in other languages

síndrome(Español)syndrome(Français)Syndrom(Deutsch)

Common misspellings

Also misspelled as:

  • snydrome
  • ssyndrome
  • sydnrome
  • synddrome
  • syndorme
  • syndrmoe
  • syndroem
  • syndromme
  • syndrrome
  • synndrome
  • synrdome
  • syyndrome
  • ysndrome

Misspelling Pattern Breakdown

How far each generated variant is from the correct spelling of syndrome - expressed in single-character edits (insert, delete, or swap one letter). Bigger bars stand out at a glance; a one-edit slip is the hardest to catch.

snydrome2ssyndrome1sydnrome2synddrome1syndorme2syndrmoe2syndroem2syndromme1
Edit distance from "syndrome"

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "syndrome"?
"syndrome" is spelled S-Y-N-D-R-O-M-E. The IPA pronunciation is /ˈsɪndɹəʊm/.
What does "syndrome" mean?
As a noun, "syndrome" means: A recognizable pattern of signs, symptoms and/or behaviours, especially of a disease or medical or psychological condition.
What are common misspellings of "syndrome"?
Common misspellings include "snydrome", "ssyndrome", "sydnrome", "synddrome", "syndorme". The correct spelling is "syndrome".
How do you pronounce "syndrome"?
The IPA (International Phonetic Alphabet) transcription for "syndrome" is /ˈsɪndɹəʊm/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "syndrome"?
Learned borrowing from New Latin syndrome, from Ancient Greek συνδρομή (sundromḗ, “concurrence of symptoms, concourse”), from σύνδρομος (súndromos, “running together”), from συν- (sun-, “with”) + δρόμος (drómos, “running, course”). See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "syndrome", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 8 letters (nearest by frequency rank).

stealing#4,897settings#4,893quarters#4,881Margaret#4,872

Similar misspelling depth

Headwords with a similar count of attested misspellings (13 here; floor ≥5).

Argentina13 variantsBaltimore13 variantsdeparture13 variantscoalition13 variants

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list