phosphodiesterase
"phosphodiesterase" is a 17-letter English headword indexed on PlainSpell.
The verdict
“phosphodiesterase” is uncommon English (frequency #88,710 among 46,516 “P” headwords), classed as a noun. The kind of spelling people second-guess.
- #88,710
- frequency rank, English
- 46,516
- “P” headwords
According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - Any of a family of enzymes that catalyze the cleavage of phosphodiester links in nucleic acids.
Corpus desk
Index EN-phosphodiesterase · phosphodiesterase · English
phosphodiesterase · rank #88,710 · 0 variants · 0 confusables
- FREQ-RARE #88,710
- LEN-MEGA 17 letters
- VOW-7 7 vowels
- CONFUS-0 No pairs
- VAR-0 0 variants
- BOOK-DENSE 46,516
- PHOTO-FINISH philately
Nearest frequency peer: philately (-1 rank slots)
Read with this headword: Spelling guide for this pattern
Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.
Frequency neighbourhood for “phosphodiesterase”
Lower corpus rank = more everyday usage (inverted bar length for readability)
- pharaonic
pharaonic
11,293 corpus weight
- philately
philately
11,292 corpus weight
- phosphodies…
phosphodiesterase
11,291 corpus weight
- photoelectr…
photoelectron
11,290 corpus weight
- pilfer
pilfer
11,288 corpus weight
- pinta
pinta
11,287 corpus weight
What this shows Bars show where “phosphodiesterase” sits against the nearest ranked English headwords in the FrequencyWords band, not a reprint of letter-browse containment.
| Property | Value |
|---|---|
| Headword | phosphodiesterase |
| Language | English |
| Part of speech | Noun |
| Letters | 17 |
| Frequency rank | #88,710 |
| Misspellings tracked | 0 |
| Confusable pairs | 0 |
| Source | Wiktionary (kaikki.org) |
Where “phosphodiesterase” sits in English frequency
Rare enough to double-check
phosphodiesterase is uncommon English at frequency #88,710 among 46,516 “P” headwords, classed as anoun. Rarity is why readers land here mid-draft. Gloss: "Any of a family of enzymes that catalyze the cleavage of phosphodiester links in nucleic acids.".
phosphodiesterase doesn't appear in our generated misspelling index, a sign its spelling follows regular English conventions. Our confusable-pair dataset has no match for it, which usually means its spelling is distinct enough that readers don't reach for a similar-looking word instead.
Etymologically, the entry records: From phosphodiester + -ase. The correct English form is phosphodiesterase, spelled P-H-O-S-P-H-O-D-I-E-S-T-E-R-A-S-E.
Definition
- 1Any of a family of enzymes that catalyze the cleavage of phosphodiester links in nucleic acids.
Etymology
From phosphodiester + -ase.
Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.
PlainSpell is rendered directly from structured Wiktionary extracts and open word-frequency lists, no number is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of May 6, 2026. Primary sources: Wiktionary (via kaikki.org) and FrequencyWords.
Frequently Asked Questions
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Similar English words by spelling shape
Same letter count and similar misspelling depth for "phosphodiesterase", not the corpus desk frequency band.
Same letter count
Frequency-ranked English headwords with 17 letters (nearest by frequency rank).
Data Source
Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.