nucleoside

/ˈn(j)u(ː)kliəˌsaɪd/

//ˈn(j)u(ː)kliəˌsaɪd// noun

"nucleoside" is a 10-letter English headword indexed on PlainSpell.

The verdict

“nucleoside” is uncommon English (frequency #71,747 among 24,391 “N” headwords), classed as a noun. The kind of spelling people second-guess.

#71,747
frequency rank, English
24,391
“N” headwords

According to Wiktionary data (CC BY-SA, analyzed May 6, 2026) - an organic molecule in which a nitrogenous heterocyclic base (or nucleobase), which can be either a double-ringed purine or a single-ringed pyrimidine, is covalently attached to a five-carbon pento...

Corpus desk

Index EN-nucleoside · nucleoside · English

nucleoside · rank #71,747 · 0 variants · 0 confusables

  • FREQ-RARE #71,747
  • LEN-MEGA 10 letters
  • VOW-5 5 vowels
  • CONFUS-0 No pairs
  • VAR-0 0 variants
  • BOOK-DENSE 24,391
  • PHOTO-FINISH nubile

Nearest frequency peer: nubile (-1 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Frequency neighbourhood for “nucleoside”

Lower corpus rank = more everyday usage (inverted bar length for readability)

corpus weight

What this shows Bars show where “nucleoside” sits against the nearest ranked English headwords in the FrequencyWords band, not a reprint of letter-browse containment.

Source FrequencyWords open word-frequency list As of May 6, 2026
Key facts for nucleoside
PropertyValue
Headwordnucleoside
LanguageEnglish
Part of speechNoun
IPA/ˈn(j)u(ː)kliəˌsaɪd/
Letters10
Frequency rank#71,747
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Where “nucleoside” sits in English frequency

Every-word frequency runs from the handful of words we use constantly (left) to the long tail used once in a blue moon (right). nucleoside lands here:

#1#100#1K#10K#100K
← used constantlyrarely used →

Scale is logarithmic (each tick is 10× rarer). Source: FrequencyWords open word-frequency list.

Rare enough to double-check

nucleoside is uncommon English at frequency #71,747 among 24,391 “N” headwords, classed as anoun, transcribed /ˈn(j)u(ː)kliəˌsaɪd/. Rarity is why readers land here mid-draft. Gloss: "an organic molecule in which a nitrogenous heterocyclic base (or nucleobase), which can be either a double-ringed purine or a single-ringed pyrimidine, is covalently attached to a five-carbon pento...".

nucleoside has no tracked misspelling variants, a sign its spelling follows regular English conventions. No close-neighbour confusable shows up for this headword in our dataset, which usually means its spelling is distinct enough that readers don't reach for a similar-looking word instead.

Etymologically, the entry records: Probably from nucleo- + (glyc)oside. The correct English form is nucleoside, spelled N-U-C-L-E-O-S-I-D-E.

Definition

  1. 1
    an organic molecule in which a nitrogenous heterocyclic base (or nucleobase), which can be either a double-ringed purine or a single-ringed pyrimidine, is covalently attached to a five-carbon pentose sugar (deoxyribose in DNA or ribose in RNA). When the phosphate group is covalently attached to the pentose sugar, it forms a nucleotide.

Etymology

Probably from nucleo- + (glyc)oside.

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

PlainSpell is rendered directly from structured Wiktionary extracts and open word-frequency lists, no number is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of May 6, 2026. Primary sources: Wiktionary (via kaikki.org) and FrequencyWords.

Frequently Asked Questions

How do you spell "nucleoside"?
"nucleoside" is spelled N-U-C-L-E-O-S-I-D-E. The IPA pronunciation is /ˈn(j)u(ː)kliəˌsaɪd/.
What does "nucleoside" mean?
As a noun, "nucleoside" means: an organic molecule in which a nitrogenous heterocyclic base (or nucleobase), which can be either a double-ringed purine or a single-ringed pyrimidine, is covalently attached to a five-carbon pento...
How do you pronounce "nucleoside"?
The IPA (International Phonetic Alphabet) transcription for "nucleoside" is /ˈn(j)u(ː)kliəˌsaɪd/. Click the speaker icon on the pronunciation badge above to hear it spoken aloud where audio is available.
What is the origin of the word "nucleoside"?
Probably from nucleo- + (glyc)oside. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "nucleoside", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 10 letters (nearest by frequency rank).

Data Source

Wiktionary (via kaikki.org), licensed under CC BY-SA & GFDL. Word ordering uses an open word-frequency list; misspelling variants are generated by edit-distance from the correct headword.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list