immunocompromise

noun

"immunocompromise" is a 16-letter English headword indexed on PlainSpell.

The verdict

“immunocompromise” is uncommon English (outside the top frequency list), classed as a noun. The kind of spelling people second-guess.

Unranked
below top-frequency English
16
letters

According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - The state of having a compromised immune system.

Corpus desk

Index EN-immunocompromise · immunocompromise · English

immunocompromise · unranked · 0 variants · 0 confusables

  • FREQ-UNRANKED Unranked
  • LEN-MEGA 16 letters
  • VOW-7 7 vowels
  • CONFUS-0 No pairs
  • VAR-0 0 variants
  • BOOK-THIN "I" thin
  • PHOTO-UNK Peer pending

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Key facts for immunocompromise
PropertyValue
Headwordimmunocompromise
LanguageEnglish
Part of speechNoun
Letters16
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Long-tail rank of “immunocompromise” in English

immunocompromisefalls outside the top-100,000 ranked English words, the long-tail zone of technical, archaic, or low-frequency vocabulary, exactly where readers second-guess spellings most.

Beyond rank #100,000. Source: FrequencyWords open word-frequency list.

Rare enough to double-check

immunocompromise is uncommon English outside the top frequency list, classed as anoun. Rarity is why readers land here mid-draft. Gloss: "The state of having a compromised immune system.".

immunocompromise has no tracked misspelling variants, a sign its spelling follows regular English conventions. This entry stands alone in our confusable dataset, since nothing in our dataset looks or sounds close enough to cause mix-ups.

Etymologically, the entry records: From immuno- + compromise. The correct English form is immunocompromise, spelled I-M-M-U-N-O-C-O-M-P-R-O-M-I-S-E.

Definition

  1. 1
    The state of having a compromised immune system.

Recorded use

Wiktionary example

These source excerpts show how immunocompromise appears in context. They illustrate usage; the definition above remains the entry’s reference meaning.

  1. Some types of cancer can lead to immunocompromise.

Etymology

From immuno- + compromise.

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "immunocompromise"?
"immunocompromise" is spelled I-M-M-U-N-O-C-O-M-P-R-O-M-I-S-E.
What does "immunocompromise" mean?
As a noun, "immunocompromise" means: The state of having a compromised immune system.
What is the origin of the word "immunocompromise"?
From immuno- + compromise. See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list