lipophilic

adj

By · According to Wiktionary data (CC BY-SA) ·

"lipophilic" is a 10-letter English headword indexed on PlainSpell.

The verdict

“lipophilic” is uncommon English (frequency #89,554 among 2,297 “L” headwords), classed as an adjective. The kind of spelling people second-guess.

#89,554
frequency rank, English
2,297
“L” headwords

According to Wiktionary data (CC BY-SA, analyzed September 3, 2026) - Having the quality of dissolving in lipids; typically composed of mostly nonpolar bonds.

Corpus desk

Index EN-lipophilic · lipophilic · English

lipophilic · rank #89,554 · 0 variants · 0 confusables

  • FREQ-RARE #89,554
  • LEN-MEGA 10 letters
  • VOW-4 4 vowels
  • CONFUS-0 No pairs
  • VAR-0 0 variants
  • BOOK-MID 2,297
  • PHOTO-FINISH ligase

Nearest frequency peer: ligase (-3 rank slots)

Read with this headword: Spelling guide for this pattern

Desk codes from Wiktionary headword shape, FrequencyWords rank tier, confusable-pair count, generated misspelling depth, letter-cohort book size, and photo-finish peer. Not a difficulty grade.

Long-tail ranks near “lipophilic”

Sparse band: bars invert rank so rarer forms read shorter

corpus weight

What this shows Long-tail view: where “lipophilic” sits against similarly uncommon English ranks.

Source FrequencyWords open word-frequency list As of September 3, 2026
Key facts for lipophilic
PropertyValue
Headwordlipophilic
LanguageEnglish
Part of speechAdjective
Letters10
Frequency rank#89,554
Misspellings tracked0
Confusable pairs0
SourceWiktionary (kaikki.org)

Long-tail rank of “lipophilic” in English

Word frequency stretches from the small set of words we reach for constantly (left) out to the long tail barely used once in a while (right).lipophilicfalls in this rarity band:

#1#100#1K#10K#100K
← used constantlyrarely used →

The axis is logarithmic, with each marked tick roughly ten times rarer than the last. Rare peers in the same band: “ligase” (#89,551), “livability” (#89,557), “Livi” (#89,558). Among 2,297 “L” headwords, “lipophilic” is #89,554. Source: FrequencyWords open word-frequency list.

Rare enough to double-check

lipophilic is uncommon English at frequency #89,554 among 2,297 “L” headwords, classed as anadjective. Rarity is why readers land here mid-draft. Gloss: "Having the quality of dissolving in lipids; typically composed of mostly nonpolar bonds.".

We couldn't generate a plausible misspelling set for lipophilic, typically a sign the spelling maps closely to how the word sounds. It is not paired with a close-neighbour confusable in our dataset, since nothing in our dataset looks or sounds close enough to cause mix-ups.

Etymologically, the entry records: From lipo- (“lipid”) + -philic (“loving”). The correct English form is lipophilic, spelled L-I-P-O-P-H-I-L-I-C.

Definition

  1. 1
    Having the quality of dissolving in lipids; typically composed of mostly nonpolar bonds.

Etymology

From lipo- (“lipid”) + -philic (“loving”).

Antonyms

hydrophilic

This word in other languages

lipofílico(Español)liposoluble(Français)lipophil(Deutsch)

Definitions, pronunciation, and etymology for this entry are drawn from Wiktionary via the kaikki.org structured extract (CC BY-SA); frequency ordering uses the FrequencyWords open word-frequency list (2018 English corpus, MIT). See the methodology for how each field is sourced and updated.

Frequently Asked Questions

How do you spell "lipophilic"?
"lipophilic" is spelled L-I-P-O-P-H-I-L-I-C.
What does "lipophilic" mean?
As an adjective, "lipophilic" means: Having the quality of dissolving in lipids; typically composed of mostly nonpolar bonds.
What is the origin of the word "lipophilic"?
From lipo- (“lipid”) + -philic (“loving”). See the full etymology section above for more details.
Is PlainSpell free to use?
Yes, PlainSpell is a completely free word reference. You can look up definitions, pronunciations, confusable pairs, homophones, and spelling corrections across 5 languages without any sign-up or subscription.

Similar English words by spelling shape

Same letter count and similar misspelling depth for "lipophilic", not the corpus desk frequency band.

Same letter count

Frequency-ranked English headwords with 10 letters (nearest by frequency rank).

livability#89,557Letourneau#89,546Macdonnell#89,578klebsiella#89,527

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list