enzymevsenzymesWhat's the difference?

Which to use

“enzyme” and “enzymes” are a confusable French pair: similar on the page, but distinct in meaning, check the gloss before you choose.

#27,428
“enzyme” frequency rank
#24,209
“enzymes” frequency rank
51637
confusion score

Side-by-Side Comparison

Feature enzyme enzymes
Definition Molécule biologique, généralement une protéine (parfois un ARN, appelé ribozyme), qui catalyse une réaction biochimique spécifique, transformant un ou plusieurs substrats en un ou plusieurs produits. Pluriel de enzyme.

Same sound, different letters: enzyme vs enzymes

Muted letters are shared; highlighted letters are the only spelling cue when pronunciation matches. Shared run: 6 letters.

6 ch
enzyme
7 ch
enzymes

Homophone desk: enzyme vs enzymes

This is the hard kind. enzyme and enzymes are pronounced identically (\ɑ̃.zim\) and both work as anoun. Neither the ear nor the grammar will rescue you; only the meaning does, so the glosses below are the whole decision. They differ by 1 extra letter(s) - “enzyme” sits inside “enzymes”. Our composite confusion score for this pair is 51637, derived from the frequency rank of both members and their visual similarity.

enzyme is recorded at frequency rank #27,428, classified as anoun, pronounced \ɑ̃.zim\. enzymes is at rank #24,209, tagged as anoun, pronounced \ɑ̃.zim\.

Glosses for this pair are partially populated in our dataset, but the full side-by-side definitions above should still guide you to the right choice.

With a confusion score of 51637, this pair ranks #153,541 of 440,172 scored French confusable pairs - roughly mid-pack for confusability.

Orthographic DNA of enzyme vs enzymes

Shared letters: emnyz. Private to "enzyme": -. Private to "enzymes": s.

"enzyme" · 6 letters · shape VCCVCV  ·  "enzymes" · 7 letters · shape VCCVCVC

Known mistypes of this pair

  • enzymeennzyme · enyzme · enzmye · enzyem · enzymme · enzyyme · enzzyme · eznyme
  • enzymesennzymes · enyzmes · enzmyes · enzyems · enzymess · enzymmes · enzymse · enzyymes

Frequently Asked Questions

Can "enzyme" and "enzymes" be used interchangeably?
No. They are pronounced the same (\ɑ̃.zim\), which is exactly why they get swapped in writing, but the dictionary meanings above are different, and pronunciation is no guide here.
Frequency check: "enzyme" vs "enzymes" - which ranks higher?
"enzymes" is the more common of the two: it sits at frequency rank #24,209 in our French list, against #27,428 for "enzyme". The two are close in frequency, so neither is a safe default; check the meaning rather than guessing.

Useful next steps

"enzyme" and "enzymes" share a sound, keep the gloss open, then jump to the headword or a nearby trap.

  • Full dictionary entry for "enzyme" with definition, IPA, and generated misspellings. Word entry
  • Full dictionary entry for "enzymes" - compare definitions side by side with the headword page. Word entry
  • This pair ranks #153,541 of 440,172 scored French confusable pairs in this corpus vintage. Corpus statistics
  • "enzyme" and "enzymes" also get mixed up with nearby pairs, the highest-scored neighbour is "enorme vs enzyme". Nearby pair
  • Recorded mistypes exist for at least one side of this pair, useful when a spell-checker or OCR lands on the wrong form. See mistypes

Confusion rank #153,541 of 440,172 scored French pairs, corpus vintage 2026-09-03, not spelling advice.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list