# Smith-Lemli-Opitz syndrome

> English word · Noun

## Definitions
1. A congenital failure of cholesterol synthesis, with effects ranging from mild intellectual disability to lethal malformations.

## Etymology
Named after David Weyhe Smith, Luc Lemli, and John Marius Opitz, three researchers who described it.

## Source
Compiled from Wiktionary via kaikki.org (CC BY-SA). Data vintage: 2026-05-06.
Canonical page: https://plainspell.com/en/word/smith-lemli-opitz-syndrome